Purpose. To evaluate the ocular pharmacokinetic properties of subretinal conbercept injection in vitrectomized rabbit eyes and to compare them with those by intravitreal injection. Methods.
Teng-teng Yao +6 more
doaj +1 more source
Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core +1 more source
Evaluation of pain during intravitreal Ozurdex injections vs intravitreal bevacizumab injections [PDF]
The purpose was to evaluate the pain associated with intravitreal Ozurdex injections, and to compare it with that associated with intravitreal bevacizumab injections.The study included 57 eyes of 57 patients who received an intravitreal Ozurdex injection at our institution. Pain was measured by the visual analog scale (VAS).
E, Moisseiev +5 more
openaire +2 more sources
Scleral abscess after intravitreal bevacizumab and triamcinolone injection
We report a case of 61-year-old male who presented with scleral abscess, an unusual complication following intravitreal bevacizumab and triamcinolone injection.
Preetam M Samant +2 more
doaj +1 more source
Choroidal Effusion following Intravitreal Brolucizumab Injection: A Case Report
This report describes a case of choroidal effusion after intravitreal brolucizumab injection for wet age-related macular degeneration (AMD). A 71-year-old Korean man with a history of wet AMD visited our clinic.
Ha Eun Sim, Jae Suk Kim, Je Hyung Hwang
doaj +1 more source
Intravitreal Cotton Fiber Foreign Body after Intravitreal Injection
Iatrogenic intraocular foreign bodies (IOFBs) are rare findings to be associated with sterile intraocular procedures. They are usually observed in the anterior chamber, introduced during cataract surgery, while IOFBs in the posterior segment of the eye are very rare.
Fran Drnovšek, Xhevat Lumi
openaire +3 more sources
Multiple Intravitreal Liposomal Amphotericin B for a Case of Candida glabrata Endophthalmitis
We report a case of Candida glabrata endophthalmitis which was effectively treated by intravitreal liposomal amphotericin B (L-AMB) injection. A 72-year-old man was referred to our department for positive blood culture of Candida glabrata.
Daiki Sakai +2 more
doaj +1 more source
Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto +5 more
core +1 more source
Intravitreal and Subconjunctival Melphalan for Retinoblastoma in Transgenic Mice
Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg
Nisha V. Shah +7 more
doaj +1 more source
Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]
The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico +5 more
core +1 more source

