Results 31 to 40 of about 31,779 (227)

Effectiveness of aflibercept in treating bevacizumab resistant macular edema [PDF]

Basrah Journal of Surgery
Aim Method Prospective study on patients with macular edema secondary to diabetes mellitus, retinal vein occlusion or wet AMD. All the patients enrolled in the study had partial or no response to bevacizumab represented by mild or no improvement
Hussain Khudair Yassin
doaj   +1 more source

Intravitreal brimonidine inhibits form-deprivation myopia in guinea pigs

Eye and Vision, 2021
Background The use of ocular hypotensive drugs has been reported to attenuate myopia progression. This study explores whether brimonidine can slow myopia progression in the guinea pig form-deprivation (FD) model.
Yifang Yang, Junshu Wu, Defu Wu, Qi Wei, Tan Zhong, Jun Yang, Xiaowei Yang, Meizhen Zeng, Xingwu Zhong   +8 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Subconjunctival anaesthesia for intravitreal injections [PDF]

Eye, 2013
Sir, We read with interest the paper by Lyall et al,1 who report the results of an observational study of infective endophthalmitis in the United Kingdom following intravitreal anti-VEGF injection. Using 200 patients selected from 10 control centres, the authors identified 3 endophthalmitis patients, compared to 1 control patient, who had ...
Alexander, P., Sahu, D., Lotery, A.J.
openaire   +3 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Topical antibiotics and intravitreal injections [PDF]

Acta Ophthalmologica, 2017
AbstractThere is increasing evidence that topical antibiotics, given before and/or after intravitreal injections, are ineffective in preventing endophthalmitis and are possibly harmful. In addition to the lack of efficacy and increased development of resistant organisms, the use of topical antibiotics adds significantly to the cost of delivering ...
Hunyor, Alex P., Merani, Rohan, Darbar, Archie, Korobelnik, Jean François, LANZETTA, Paolo, Okada, Annabelle A.   +5 more
openaire   +3 more sources

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Intravitreal silicone oil droplet after intravitreal injection

Journal of Retina-Vitreous, 2022
Currently, anti-vascular endothelial growth factor agents (anti-VEGF) are frequently used in the treatment of diseases such as age-related macular degeneration and diabetic macular edema. In our study, we discussed three cases in which intravitreal silicone oil droplets were detected during the follow-up after intravitreal anti-VEGF agent ...
Çetin, Ebru Nevin, Pekel, Gökhan, Akbulut, Selen   +2 more
openaire   +2 more sources

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

Advanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao, Xiaoyu Li, Hongwei Wang, Zongyi Li, Qun Wang, Yangyang Zhang, Xu Jing, Xia Qi, Qingjun Zhou, Shengqian Dou, Lixin Xie   +10 more
wiley   +1 more source

Embryonic Intravitreous Injection in Mouse

BIO-PROTOCOL, 2018
Axons of retinal ganglion cells (RGCs) relay visual information from the retina to lateral geniculate nucleus (LGN) and superior colliculus (SC), which are two major image-forming visual nuclei. Wiring of these retinal projections completes before vision begins.
Liyuan Cui, Yupu Diao, Jiayi Zhang
openaire   +4 more sources