Intravitreal injection represents the primary method of drug administration for a range of common chronic endophthalmic diseases, including age-related macular degeneration, diabetic retinopathy and retinal vein occlusion.Recognized for its high clinical
Group Standards Team of SOP and Quality Control Standards for Intravitreal Injection in Guangdong
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Alterations in intraocular pressure and ocular axial length after intravitreal Anti-VEGF injection [PDF]
Objective: To evaluate the effect of intravitreal anti-vascularendothelial growth factor (anti-VEGF) injection onintraocular pressure (IOP) and ocular axial length (AL).Methods: A prospective series of consecutive patientsundergoing injection of ...
Baran Gencer +5 more
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Self-sealing hyaluronic acid (HA)-coated self-sealing 30-gauge needles exhibiting instant leakage prevention of intravitreal humor and injected drug were developed in this study. Ninety New Zealand rabbits were used in this study.
Youngsub Eom +10 more
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Intracameral Injection of Bevacizumab for the Treatment of Neovascular Glaucoma [PDF]
Purpose: To assess the duration of the effect of intracameral bevacizumab in patients presenting with rubeosis iridis and neovascular glaucoma (NVG). Methods: Retrospective analysis of 24 consecutive eyes of 24 patients with decompensated NVG (> 21 mm Hg)
Haritoglou, Christos +3 more
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Exogenous Endophthalmitis: Post-Operative versus Post-Intravitreal Injection
Endophthalmitis is a potentially vision-threatening complication associated with nearly every intraocular or periocular procedure, including cataract surgery and intravitreal injection.
Jennifer L Rizzo +3 more
doaj +1 more source
Ultrastructural changes in the rabbit retina after various one-time doses of intravitreal melphalan
Background: Intravitreal chemotherapy (IVC) has become a common eye-preserving treatment for retinoblastoma (RB). However, there are still unsolved issues with regard to dosage of the cytostatic agent, its ultrastructural effects on healthy retinal cells,
N.F. Bobrova +3 more
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Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson +8 more
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Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery +30 more
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Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]
PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David +13 more
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Factors associated with extended remission in neovascular age-related macular degeneration on pro re nata treatment protocol. [PDF]
AimTo show the characteristics and outcomes of patients with neovascular age-related macular degeneration (nAMD) who had extended remission (ER) while on a pro re nata (PRN) treatment protocol.MethodsThis was a retrospective case-control study of a ...
Amador-Patarroyo, Manuel J +6 more
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