Results 71 to 80 of about 715,934 (265)

Efficacy and safety of prophylactic simultaneous intravitreal moxifloxacin injection with standard intravitreal anti-VEGF injection procedure in cases of cystoid macular edema and macular neovascularization

BMC Ophthalmology
Background To investigate the safety and efficacy of prophylactic use of commercially available intravitreal moxifloxacin 0.5% (Vigamox) at the time of intravitreal anti-VEGF injection against post-injection infectious endophthalmitis.
Mohamed Nagy Elmohamady, Ahmed Sherin Mustafa Bayoumy, Ahmed Abd Elmeguid Khater, Husam Mustafa Faramawi   +3 more
doaj   +1 more source

Intravitreal injections: A brief note

Kerala Journal of Ophthalmology, 2018
The delivery of medications directly into the vitreous cavity through an injection or implant has become a commonplace in ophthalmology. Common diseases treated by intravitreal injections include neovascular age-related macular degeneration, clinically ...
Anu Joseph
doaj   +1 more source

Six month delivery of GDNF from PLGA/vitamin E biodegradable microspheres after intravitreal injection in rabbits [PDF]

, 2017
Local long-term delivery of glial cell line derived neurotrophic factor (GDNF) from vitamin E/poly-lactic-co-glycolic acid microspheres (MSs) protects retinal ganglion cells in an animal model of glaucoma for up to 11 weeks. However, the pharmacokinetics
Prieto Calvo, Esther, Herrero Vanrell, María Del Rocío, Esther Prieto-Calvo, Rocío Herrero-Vanrell, Polo Llorens, Vicente, García-Feijoo, J., Checa Casalengua, Patricia, Molina Martínez, Irene Teresa, Checa-Casalengua, P., García Caballero, Cristina G., García-Caballero, C., Patricia Checa-Casalengua, Irene Teresa Molina-Martínez, Molina-Martínez, I.T., Bravo Osuna, Irene, García Feijoo, Julián, Cristina García-Caballero, Irene Bravo-Osuna, García Martín, Elena Salobrar, Herrero-Vanrell, R., Polo-Llorens, V., Julián García-Feijoo, Bravo-Osuna, I., Elena García-Martín, Vicente Polo-Llorens, García-Martín, E., Prieto-Calvo, E.   +26 more
core   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Short-term efficacy of intravitreal triamcinolone acetonide for macular edema secondary to retinal vein occlusion that is refractory to intravitreal bevacizumab

Indian Journal of Ophthalmology, 2015
Aims: To evaluate the 1-month efficacy of intravitreal triamcinolone acetonide (TA) in treating macular edema secondary to retinal vein occlusion (RVO) that was refractory to intravitreal bevacizumab.
Seul Gi Yoo, Jae Hui Kim, Tae Gon Lee, Chul Gu Kim, Jong Woo Kim   +4 more
doaj   +1 more source

The impact of coronary artery bypass grafting on the short‐ and long‐term development and progression of diabetic retinopathy: A Danish national matched cohort study

Acta Ophthalmologica, EarlyView.
Abstract Purpose Diabetic retinopathy (DR) is a frequent long‐term complication of diabetes. While hemodynamic changes are known risk factors for DR, the effect of coronary artery bypass grafting (CABG) on the development of DR is poorly investigated.
Lukas Greve Maschoreck, Lonny Stokholm, Frederik Nørregaard Pedersen, Nis Andersen, Jens Andresen, Toke Bek, Sebastian Dinesen, Javad Hajari, Steffen Heegaard, Kurt Højlund, Caroline Schmidt Laugesen, Ryo Kawasaki, Sören Möller, Katja Christina Schielke, Yousif Subhi, Anne Suhr Thykjær Petersen, Jakob Grauslund   +16 more
wiley   +1 more source

Exploring market dynamics of biological including biosimilar treatments for retinal diseases in Europe: An interrupted time‐series analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the impact of biosimilar ranibizumab and on‐patent faricimab market entry on pricing and utilization trends and describe national variation in off‐label bevacizumab use in Europe. Methods Interrupted time series analysis of quarterly sales data (Q1 2018–Q2 2024) in 11 European countries evaluated ranibizumab utilization and ...
Elif Car, Isabelle Huys, Steven Simoens, Arnold G. Vulto   +3 more
wiley   +1 more source

Safety of intravitreal triamcinolone acetonide:an electrophysiologic and histopathological study in rabbits

International Journal of Ophthalmology, 2013
AIM: To evaluate the retinal safety of various doses of intravitreal triamcinolone acetonide (TA) in rabbits.Methods: Thirty New Zealand albino rabbits were divided into five groups (six animals each).
Laila Hassan M. El-Shazly , Amal Ahmad El-Gohary , Ghada Ghanem El-Hossary   +2 more
doaj   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

Acta Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco, Nisa Silva, Camiel J. F. Boon   +2 more
wiley   +1 more source