A paracentesis prior to an intravitreal injection is a very safe procedure and can prevent IOP-spikes after injections. As these spikes pose the risk of inducing glaucomatous changes particularly in patients with frequent injections and/or with a risk ...
S. Saxena +41 more
semanticscholar +1 more source
Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]
PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David +13 more
core +2 more sources
Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul +6 more
core +1 more source
Importance The number of patients affected by retinal diseases treated with intravitreal injections (IVTs) has resulted in a rapidly growing number of procedures. One of the worst complications after these injections is endophthalmitis.
F. Baudin +7 more
semanticscholar +1 more source
Intravitreal injection of Ozurdex(®) implant in patients with persistent diabetic macular edema, with six-month follow-up [PDF]
AIM: To evaluate the efficacy of intravitreal dexamethasone injections in diabetic macular edema (DME). METHODS: A 700 μg slow-release intravitreal dexamethasone implant (Ozurdex®) was placed in the vitreal cavity of 17 patients (19 eyes) affected ...
Bottone, A +8 more
core +2 more sources
State and Trait Anxiety Scores of Patients Receiving Intravitreal Injections
Background: To evaluate parameters on the state and trait anxiety scores of patients receiving intravitreal injections. Methods: One hundred thirteen patients were included in the study.
O. Kayikcioglu +3 more
semanticscholar +1 more source
Intravitreal injections, antibiotics and endophthalmitis [PDF]
Sir, The article by Lyall et al1 entitled ‘Post-intravitreal anti-VEGF endophthalmitis in the United Kingdom: incidence, features, risk factors, and outcomes' is timely, given current efforts to minimize the risk of endophthalmitis following intravitreal injections.
A R, Bhavsar, D R, Sandler, R C, Gentile
openaire +2 more sources
Long-Term Intravitreal Ranibizumab as a Potential Additional Risk Factor for Neurodegeneration in Parkinson's Disease: A Case Report. [PDF]
In November 2012, a 72-year old patient was diagnosed with left eye wet age-related macular degeneration. The patient received three monthly intravitreal injections of ranibizumab, with complete resolution of retinal hemorrhage and edema and ...
Antonini +43 more
core +2 more sources
Intravitreal Anti-VEGF Drugs and Signals of Dementia and Parkinson-Like Events: Analysis of the VigiBase Database of Spontaneous Reports [PDF]
Introduction: Since vascular endothelial growth factor (VEGF) regulates several aspects of the central nervous system, particularly in dopaminergic neurons, VEGF inhibitors may be linked to Parkinson-like events and dementia, or variants of these ...
Avery +30 more
core +4 more sources
Current Evidence for the Prevention of Endophthalmitis in Anti-VEGF Intravitreal Injections
Intravitreal injection of a therapeutic substance is the most common procedure performed in ophthalmology. It has a low incidence of serious complications but is associated with a small chance of endophthalmitis.
P. Lau +2 more
semanticscholar +1 more source

