Results 91 to 100 of about 90,190 (300)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
A 57‐Year‐Old Male With Behavioral Variant Frontotemporal Dementia and MATR3 and NOS3 Mutations
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT This report presents a case of behavioral variant frontotemporal dementia caused by mutations in the MATR3 and NOS3 genes, aiming to analyze its clinical manifestations and genetic characteristics. For a case presenting with personality changes and gait abnormalities as the initial symptoms, this study conducted a comprehensive analysis of its
Feifei Lin, Saie Huang
wiley +1 more source
ADMET and DMPK, 2014 The purpose of the study was to assess the stoichiometries of phosphate precipitates and determine the intrinsic solubilities, S0, of 25 basic drugs from their published solubility-pH profiles in the landmark study of Bergström et al.
Alex Avdeef
doaj +1 more source
Advanced Engineering Materials, EarlyView.Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
Wave and Maxwell's equations in Carnot groups
, 2012 In this paper we define Maxwell’s equations in the setting of the intrinsic complex of differential forms in Carnot groups introduced by M. Rumin. It turns out that these equations are higher-order equations in the horizontal derivatives.
FRANCHI, BRUNO, TESI, MARIA CARLA
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Advanced Engineering Materials, EarlyView.The corrosion performance of AlSi7Mg and AlSi10Mg alloys produced through selective laser melting (SLM) was examined under compressive stress in a chloride environment. Electrochemical analyses, including open‐circuit potential (OCP), potentiodynamic polarization (CPP), and electrochemical impedance spectroscopy (EIS), were complemented by scanning ...
Femi John Akinfolarin +2 more
wiley +1 more source
Intrinsic Solution on Quadratic Diophantine Equation
International Journal for Research in Applied Science and Engineering TechnologyAbstract: The non-zero unique integer solutions of the Quadratic Diophantine Equation with three ...
openaire +1 more source
Advanced Engineering Materials, EarlyView.This study demonstrates an efficient recycling route for out‐of‐spec AlSi10Mg atomized powders through compaction and arc remelting followed by suction casting. By correlating compaction load, cooling rate, and resulting microstructure, we show that intermediate pressures (50–80 kN) and rapid cooling refine dendrites, reduce porosity, and enhance ...
Mila Christy de Oliveira +4 more
wiley +1 more source
A Note on Solutions for the Intrinsic Generalized Wave and Sine-Gordon Equations
, 1989 Tenenblat, Keti. (1989). A Note on Solutions for the Intrinsic Generalized Wave and Sine-Gordon Equations.
Tenenblat, Keti
core
Doubly nonlinear parabolic equations
, 2020 The public defense on 15th May 2020 at 12:00 will be organized via remote technology. Link: https://aalto.zoom.us/j/66291986278 Zoom Quick Guide: https://www.aalto.fi/en/services/zoom-quick-guideThis thesis is devoted to the study of the existence and ...
Vestberg, Matias
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