Results 91 to 100 of about 15,218,319 (382)

Intrinsic rewards and work engagement in the South African retail industry

open access: yesSA Journal of Industrial Psychology, 2014
Orientation: There is a lack of South African research relating to the provision of intrinsic rewards to retail employees. Research purpose: The purpose of this research was to determine whether there is a relationship between intrinsic rewards and work ...
Sara Jacobs   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Single photon emission and detection at the nanoscale utilizing semiconductor nanowires

open access: yes, 2008
We report recent progress toward on-chip single photon emission and detection in the near infrared utilizing semiconductor nanowires. Our single photon emitter is based on a single InAsP quantum dot embedded in a p-n junction defined along the growth ...
Algra, Rienk   +13 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Why are some BL Lacs detected by \fermi, but others not ?

open access: yes, 2014
By cross-correlating an archival sample of 170 BL Lacs with 2 year \fermilat AGN sample, we have compiled a sample of 100 BL Lacs with \fermi detection (FBLs), and a sample of 70 non-\fermi BL Lacs (NFBLs).
Chen, Liang   +3 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

High Quality Factor Silicon Cantilever Driven by PZT Actuator for Resonant Based Mass Detection [PDF]

open access: yes, 2008
A high quality factor (Q-factor) piezoelectric lead zirconat titanate (PZT) actuated single crystal silicon cantilever was proposed in this paper for resonant based ultra-sensitive mass detection.
Ikehara, T.   +5 more
core   +1 more source

VLBI observations of seven BL Lac objects from RGB sample

open access: yes, 2007
We present EVN observations of seven BL Lac objects selected from the RGB sample. To investigate the intrinsic radiation property of BL Lac objects, we estimated the Doppler factor with the VLA or MERLIN core and the total 408 MHz luminosity for a sample
Albert   +61 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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