Results 71 to 80 of about 15,038,588 (334)

Consistency of Bayes factor for nonnested model selection when the model dimension grows

open access: yes, 2016
Zellner's $g$-prior is a popular prior choice for the model selection problems in the context of normal regression models. Wang and Sun [J. Statist. Plann.
Maruyama, Yuzo, Wang, Min
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Factor XII (Hageman Factor) Deficiency: a rare harbinger of life threatening complications

open access: yesThe Pan African Medical Journal, 2019
Hageman factor (factor XII) has a key role in activation of intrinsic coagulation system gauged by activated partial thromboplastin time (aPPT)).
Liaqat Ali Chaudhry   +3 more
doaj   +1 more source

Consistency of Bayesian procedures for variable selection

open access: yes, 2009
It has long been known that for the comparison of pairwise nested models, a decision based on the Bayes factor produces a consistent model selector (in the frequentist sense).
Elías Moreno   +4 more
core   +2 more sources

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Analysis of equivalent circuit of test of intrinsic safety circuit

open access: yesGong-kuang zidonghua, 2013
Taking an intrinsic safety circuit of passive rescue telephone as an example, the paper analyzed test process of safe spark test of the circuit under different electrical principle equivalent diagrams of intrinsic safety test, and indicated that spark ...
LIU Qi
doaj   +1 more source

Validity and reliability of the Academic Motivation Scale in a sample of Slovenian students [PDF]

open access: yesPsihološka Obzorja, 2017
In this study we examined construct validity and reliability of the Academic Motivation Scale, College Version (Academic Motivation Scale, AMS-C 28, Vallerand et al., 1992) and its relationship with gender, certainty of study choice and career goals in ...
Melita Puklek Levpušček, Anja Podlesek
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

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