Results 81 to 90 of about 1,836,928 (287)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Nature of the Intrinsic Factor of Castle [PDF]

, 1950
B. E. Hall
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

The Diagnostic Value of Anti-Parietal Cell and Intrinsic Factor Antibodies, Pepsinogens, and Gastrin-17 in Corpus-Restricted Atrophic Gastritis. [PDF]

Diagnostics (Basel), 2022
Kriķe P, Shums Z, Poļaka I, Kikuste I, Vanags A, Tolmanis I, Isajevs S, Liepniece-Karele I, Santare D, Tzivian L, Rudzīte D, Song M, Camargo MC, Norman GL, Leja M.   +14 more
europepmc   +1 more source

Quantitative Assay of Intrinsic Factor Activity by Urinary Excretion of Radioactive Vitamin B12 [PDF]

, 1958
Leon Ellenbogen, William L. Williams
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Intrinsic factor autoantibodies by luminescent immuno-precipitation system in patients with corpus atrophic gastritis. [PDF]

J Transl Autoimmun, 2021
Marzinotto I, Dottori L, Baldaro F, Dilaghi E, Brigatti C, Bazzigaluppi E, Esposito G, Davidson HW, Piemonti L, Lampasona V, Lahner E.   +10 more
europepmc   +1 more source

Concentration of Intrinsic Factor and Vitamin B12-Binding Activities of Fractions of Desiccated Hog Stomach [PDF]

, 1953
William H. Prusoff, Arnold D. Welch, Robert W. Heinle, GORDON C. MEACHAM   +3 more
openalex   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

COMBINED CORD DEGENERATION WITHOUT ANEMIA: A CASE REPORT WITH STUDIES BEARING ON THE “INTRINSIC FACTOR” OF CASTLE [PDF]

, 1936
Walter L. Palmer, Robert T. Porter
openalex   +1 more source