Results 71 to 80 of about 410,177 (299)

A Chaotic State in the Transition From Single Toward Multiple Pulse for Soliton Fiber Lasers

IEEE Photonics Journal, 2020
High-order soliton in anomalous-dispersion ultrafast fiber lasers is rarely researched due to its intrinsic instability in dissipative systems. For the first time, we numerically demonstrate the ultrafast pulse in fiber lasers will deviate from the ...
Yueqing Du, Mengmeng Han, Xuewen Shu
doaj   +1 more source

Instabilities and Topological Defects in Active Nematics

, 2013
We study a continuum model of an extensile active nematic to show that mesoscale turbulence develops in two stages: (i) ordered regions undergo an intrinsic hydrodynamic instability generating walls, lines of stong bend deformations, (ii) the walls relax
Golestanian, Ramin, Thampi, Sumesh P., Yeomans, Julia M.   +2 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Modified Arthroscopic Volar Scapholunate Capsuloligamentous Repair in Chronic Severe but Reducible Volar Scapholunate Instability

Arthroscopy Techniques
The scapholunate complex is composed of the intrinsic scapholunate ligament and the surrounding extrinsic ligamentous system on the dorsal and volar sides of the wrist.
Chul Ki Goorens, M.D., Kjell Van Royen, M.D.   +1 more
doaj   +1 more source

EEG state-trajectory instability and speed reveal global rules of intrinsic spatiotemporal neural dynamics.

PLoS ONE, 2020
Spatiotemporal dynamics of EEG/MEG (electro-/magneto-encephalogram) have typically been investigated by applying time-frequency decomposition and examining amplitude-amplitude, phase-phase, or phase-amplitude associations between combinations of ...
Melisa Menceloglu, Marcia Grabowecky, Satoru Suzuki   +2 more
doaj   +1 more source

Coiling Instabilities in Multilamellar Tubes

, 2002
Myelin figures are densely packed stacks of coaxial cylindrical bilayers that are unstable to the formation of coils or double helices. These myelin figures appear to have no intrinsic chirality.
C. D. Santangelo, C.-M. Chen, I. Sakurai, I. Sakurai, I. Tsafrir, I. Tsafrir, J.P. Hurault, K. Lin, K. Mishima, M. Boucif, M. Buchanan, Ou-Yang Zhong-can, P. Nelson, P. Pincus, P.G. de Gennes, R. Bar-Ziv, R. Goldstein, S. Chaieb, V. Frette, W. Helfrich, W. Helfrich   +20 more
core   +1 more source

Intrinsic flame instabilities in combustors: Analytic description of a 1-D resonator model [PDF]

, 2017
The study is concerned with theoretical examination of thermo-acoustic instabilities in combustors and focuses on recently discovered ‘flame intrinsic modes’. These modes differ qualitatively from the acoustic modes in a combustor.
Mukherjee, NK, Shrira, VI
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

Nature Communications, 2020
The majority of high grade serous ovarian cancers originate from fallopian tube secretory epithelial cells (FTSECs). Here the authors show that miR-181a drives oncogenic transformation in FTSECs through the cooperative inhibition of the tumor suppressor ...
Matthew Knarr, Rita A. Avelar, Sreeja C. Sekhar, Lily J. Kwiatkowski, Michele L. Dziubinski, Jessica McAnulty, Stephanie Skala, Stefanie Avril, Ronny Drapkin, Analisa DiFeo   +9 more
doaj   +1 more source