Results 51 to 60 of about 112,558 (261)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Arthroscopy TechniquesThe scapholunate complex is composed of the intrinsic scapholunate ligament and the surrounding extrinsic ligamentous system on the dorsal and volar sides of the wrist.
Chul Ki Goorens, M.D. +1 more
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
A Chaotic State in the Transition From Single Toward Multiple Pulse for Soliton Fiber Lasers
IEEE Photonics Journal, 2020 High-order soliton in anomalous-dispersion ultrafast fiber lasers is rarely researched due to its intrinsic instability in dissipative systems. For the first time, we numerically demonstrate the ultrafast pulse in fiber lasers will deviate from the ...
Yueqing Du, Mengmeng Han, Xuewen Shu
doaj +1 more source
Intrinsic instability of sonic white holes
, 2002 Artificial black holes, such as sonic holes in Bose-Einstein condensates, may give insights into the role of the physics at the event horizon beyond the Planck scale. We show that sonic white holes give rise to a discrete spectrum of instabilities that is insensitive to the analogue of trans-Planckian physics for Bose-Einstein condensates.
Leonhardt, U., Kiss, T., Ohberg, P.
openaire +2 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
PLoS ONE, 2020 Spatiotemporal dynamics of EEG/MEG (electro-/magneto-encephalogram) have typically been investigated by applying time-frequency decomposition and examining amplitude-amplitude, phase-phase, or phase-amplitude associations between combinations of ...
Melisa Menceloglu +2 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Nature Communications, 2020 The majority of high grade serous ovarian cancers originate from fallopian tube secretory epithelial cells (FTSECs). Here the authors show that miR-181a drives oncogenic transformation in FTSECs through the cooperative inhibition of the tumor suppressor ...
Matthew Knarr +9 more
doaj +1 more source