Results 61 to 70 of about 117,106 (293)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Association between Extrinsic and Intrinsic Carpal Ligament Injuries at MR Arthrography and Carpal Instability at Radiography: Initial Observations

, 2006
PURPOSE: To retrospectively compare the presence or absence of carpal instability on radiographs with the findings of magnetic resonance (MR) arthrographic evaluation of intrinsic and extrinsic ligament tears in patients with chronic wrist pain ...
Favarger, N., Wintermark, M., Bertrand Duvoisin, Ghazal Etechami, Gilula, L.A., Theumann, N.H., Duvoisin, B., Max Wintermark, Pierre Schnyder, Nicolas Favarger, Louis A. Gilula, Schnyder, P., Etechami, G., Nicolas H. Theumann   +13 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The effect of intrinsic instability of cantilever on static mode atomic force spectroscopy

, 2010
We show that the static force spectroscopy curve taken in an atomic force microscope is significantly modified due to presence of intrinsic cantilever instability which occurs as a result of its movement in a nonlinear force field.
Das, Soma, Sreeram, P. A., Das, S., Dietzel, D., Dietzel, Dirk, Raychaudhuri, A. K.   +5 more
core   +1 more source

A Chaotic State in the Transition From Single Toward Multiple Pulse for Soliton Fiber Lasers

IEEE Photonics Journal, 2020
High-order soliton in anomalous-dispersion ultrafast fiber lasers is rarely researched due to its intrinsic instability in dissipative systems. For the first time, we numerically demonstrate the ultrafast pulse in fiber lasers will deviate from the ...
Yueqing Du, Mengmeng Han, Xuewen Shu
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Intrinsic thermoacoustic instability in hydrogen enriched partially premixed flames

The influence of hydrogen addition on the intrinsic thermoacoustic instability in swirl stabilized partially premixed methane flames is investigated using large eddy simulation (LES) and reduced order modeling (ROM). The LES results compare well with the
Massey, James C., Soundararajan, Preethi Rajendram, Kumar, Ankit D., Swaminathan, Nedunchezhian, Boxx, Isaac   +4 more
core   +2 more sources

Modified Arthroscopic Volar Scapholunate Capsuloligamentous Repair in Chronic Severe but Reducible Volar Scapholunate Instability

Arthroscopy Techniques
The scapholunate complex is composed of the intrinsic scapholunate ligament and the surrounding extrinsic ligamentous system on the dorsal and volar sides of the wrist.
Chul Ki Goorens, M.D., Kjell Van Royen, M.D.   +1 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Intrinsic paramagnetic Meissner effect due to s-wave odd-frequency superconductivity

, 2015
In 1933, Meissner and Ochsenfeld reported the expulsion of magnetic flux-the diamagnetic Meissner effect-from the interior of superconducting lead. This discovery was crucial in formulating the Bardeen-Cooper-Schrieffer (BCS) theory of superconductivity.
Suter, A., Di Bernardo, A., S. L. Lee, Amado, M., A. Di Bernardo, M. G. Blamire, Salman, Z., X. L. Wang, J. Linder, Zhao, J. H., Z. Salman, J. W. A. Robinson, Morenzoni, E., Linder, J., Wang, X. L., Robinson, J. W. A., Blamire, M. G., A. Suter, M. G. Blamire, X. L. Wang, J. H. Zhao, M. Egilmez, J. W. A. Robinson, Flokstra, M. G., Prokscha, T., E. Morenzoni, M. G. Flokstra, M. G. Flokstra, S. L. Lee, M. Amado, J. H. Zhao, Egilmez, M., Lee, S. L., T. Prokscha   +33 more
core   +1 more source