Results 91 to 100 of about 19,735 (258)
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Intrinsic rewards explain context-sensitive valuation in reinforcement learning. [PDF]
Molinaro G, Collins AGE.
europepmc +1 more source
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Monitoring-Based Rewards Enhance Both Learning Performance and Metacognitive Monitoring Accuracy
Utilization of monetary rewards in educational settings remains contentious due to its potential adverse effects such as performance-related anxiety, metacognitive inaccuracy, and diminished intrinsic motivation.
Shaohang Liu +2 more
doaj +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
An Examination of Employee Rewards and Work Environment on Employee Creativity and Innovation
Purpose - The provision of rewards to employees for their innovative ideas and creative ideas acts as a motivational factor, encouraging them to sustain their efforts in developing novel and innovative solutions.
Dickson Mdhlalose
doaj +1 more source
Service Innovation in Human Resource Management During COVID-19: A Study to Enhance Employee Loyalty Using Intrinsic Rewards. [PDF]
Abdullah MI +3 more
europepmc +1 more source
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source
A Bird Matching Game: Difficulty, Rewards and Intrinsic Motivation
In this study the effects of several variables on intrinsic motivation and in-game progression are tested in a serious game that matches bird pictures to names. The first variables are ‘pointification’ rewards (badges and points) and educational rewards
Janne +3 more
doaj +1 more source
What Do Large Language Models Know About Materials?
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer +2 more
wiley +1 more source

