Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
When suffering becomes a game: a critical examination of gamification in medical education and its implications for compassion and empathy. [PDF]
Front Med (Lausanne)Mohiyeddini C.
europepmc +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Intrinsic rewards guide visual resource allocation via reinforcement learning
Tomić I, Raimundo R, Bays PM.
europepmc +1 more source
The influences of perceived green advertising value and motivation types on green purchasing intention. [PDF]
Front PsycholBui TH, Morimura F, Nishitani K.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
DSAC-ICM: A Distributional Reinforcement Learning Framework for Path Planning in 3D Uneven Terrains. [PDF]
Sensors (Basel)Zhou Y, Liu F, Liu Z, Ji X, Yin G.
europepmc +1 more source
Bioprinting High‐Cell‐Density Cardiac Tissue Constructs With Sustained Contractile Function
Advanced Healthcare Materials, EarlyView.Contractile cardiomyocytes in 3D culture provide insights into the behavior of the heart. Combining a 3D bioprinting approach with a multi‐electrode array allows the development of the 3D culture to be monitored over time, and matured cultures allow the effect of drugs on cardiac function to be modelled, replicating effects seen in clinical application.
Priscila Melo +8 more
wiley +1 more source
Interlinking professional skills, job satisfaction, and performance: a parallel mediation model of university counsellors. [PDF]
Sci RepCao J, Kelana BWBY, Mansor NNA, Li J.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.An electrically conductive FmocFF/MXene/hyaluronic acid hydrogel combines extracellular matrix‐like architecture, self‐healing behavior, oxidation‐resistant conductivity, and biochemical cues in a single scaffold. By enabling physiologically relevant electrical stimulation, the platform enhances fibroblast attachment, proliferation, and migration ...
Offir Loboda +7 more
wiley +1 more source