Results 81 to 90 of about 2,176,076 (280)

Measuring intrinsic value – how to stop worrying and love economics [PDF]

This paper seeks to transcend entrenched misunderstandings between economists and arts policymakers, leaders and funders. These misunderstandings, which have long dogged discussion on arts funding in the UK, are most evident in the long-running debate ...
Bakhshi, Hasan, Freeman, Alan, Hitchen, Graham   +2 more
core   +1 more source

An analysis of the durations of Swift Gamma-Ray Bursts

, 2008
We report the systematic analysis of the durations for Swift gamma-ray bursts (GRBs) and compare the results with those of pre-Swift data. For 95 GRBs with known redshift, we show that the observed durations have two lognormal distributions that are ...
Bagoly, Bagoly, Balázs, Band, Band, Bromm, Butler, C.-S. Choi, Chattopadhyay, Chen, Cheng, Daigne, Dar, Fenimore, Fishman, Ford, Friedman, Gehrels, Gehrels, Ghirlanda, Hakkila, Hakkila, Horváth, Horváth, Horváth, Huang, Jakobsson, Janiuk, Katz, Koshut, Kouveliotou, Lee, Mao, McBreen, Meegan, Mukherjee, Mészáros, Mészáros, Mészáros, Nakar, Norris, Paciesas, Piran, Ryde, Shen, Toma, Usov, Yamazaki, Yi, Z.-B. Zhang, Zhang, Zhang, Zhang, Zhang, Zhang   +54 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The power of argument: Enhancing citizen’s valuation of and attitude towards agricultural biodiversity

International Journal of Agricultural Sustainability, 2019
Agrobiodiversity has been decreasing substantially in Europe. Social scientific research in this area has paid limited attention to how citizens value agrobiodiversity and its decline, and how these valuations can be influenced.
Hens Runhaar, Piety Runhaar, Machiel Bouwmans, Simon Vink, Arjen Buijs, David Kleijn   +5 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Fundamental Analysis – Possiblity of Application on the Real Estate Market

Real Estate Management and Valuation, 2016
The most common method supporting investing on the capital market or making decisions on the real estate market is technical analysis. This article, however, focuses on the less popular fundamental analysis, the importance of which is increasing on ...
Figurska Marta, Wisniewski Radoslaw
doaj   +1 more source

Rewarding cognitive effort increases the intrinsic value of mental labor. [PDF]

Proc Natl Acad Sci U S A, 2022
Clay G, Mlynski C, Korb FM, Goschke T, Job V.   +4 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Place of Gender Stereotypes in the Network of Cognitive Abilities, Self-Perceived Ability and Intrinsic Value of School in School Children Depending on Sex and Preferences in STEM. [PDF]

Behav Sci (Basel), 2022
Ismatullina V, Adamovich T, Zakharov I, Vasin G, Voronin I.   +4 more
europepmc   +1 more source