Results 111 to 120 of about 1,852,727 (295)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Two of a Kind. Similarities Between Ranking and Rating Data in Measuring Values.
Survey Research Methods, 2016 The key research question asked in this research is to what extent the respondents’ answers to ranking a set of items is mirrored in the response pattern when using rating questions.
Guy Moors +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Exploring the relationship between spirituality and work values amongst hospitality students / Rahmat Hashim, Alina Shuhaida Mohd Ramly and Zulhan Othman [PDF]
, 2009 Recent attention to issues of holistic wholeness among employees has ignited great concern about the relevancy of traditional management thinking. It has been argued that this thinking is not sufficient to address current and future concerns about ...
Hashim, Rahmat +2 more
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Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Testing a measurement model of multidimensional intrinsic motivation in studying for examination [PDF]
, 2012 Intrinsic motivation is seen as a stronger driver for academic success compared to extrinsic motivation. This study proposed a comprehensive framework for intrinsic motivation by incorporating five different theories in a measurement model. The reason is
Elias, Habibah +3 more
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FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Theoretical study of adsorption complexes in H-ZSM-5 [PDF]
, 2010 Catalytic conversions in acidic zeolites such as H-ZSM-5 find applications in a whole range of industrial production processes. Unraveling the actual network of reactions taking place inside the zeolite pores, however, can be a very challenging task.
Hemelsoet, Karen +4 more
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