Results 241 to 250 of about 3,841,423 (288)

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Self-association and multimer formation in AtLEA4-5, a desiccation-induced intrinsically disordered protein from plants. [PDF]

Protein Sci
Romero-Pérez PS, Martínez-Castro LV, Linares A, Arroyo-Mosso I, Sánchez-Puig N, Cuevas-Velazquez CL, Sukenik S, Guerrero A, Covarrubias AA.   +8 more
europepmc   +1 more source

AlphaFold2 modeling and molecular dynamics simulations of an intrinsically disordered protein. [PDF]

PLoS One
Guo HB, Huntington B, Perminov A, Smith K, Hastings N, Dennis P, Kelley-Loughnane N, Berry R.   +7 more
europepmc   +1 more source

Encoding Structure in Intrinsically Disordered Protein Biomaterials. [PDF]

Acc Chem Res
Strader RL, Shmidov Y, Chilkoti A.
europepmc   +1 more source

Conserved and repetitive motifs in an intrinsically disordered protein drive ⍺-carboxysome assembly. [PDF]

J Biol Chem
Turnšek JB, Oltrogge LM, Savage DF.
europepmc   +1 more source

Liquid liquid phase separation of the intrinsically disordered protein JPT2 compartmentalizes components of NAADP-evoked Ca ²⁺ signaling

Kumar S, Gunaratne GS, Cornish J, Silvey KM, Mu Q, Guan Z, Heller GT, Slama JT, Patel S, Marchant JS.   +9 more
europepmc   +1 more source

From molecular descriptions to cellular functions of intrinsically disordered protein regions. [PDF]

Biophys Rev (Melville)
Chen W, Fraser OA, George C, Showalter SA.   +3 more
europepmc   +1 more source

Intrinsically Disordered Proteins: An Overview

International Journal of Molecular Sciences, 2022
Many proteins and protein segments cannot attain a single stable three-dimensional structure under physiological conditions; instead, they adopt multiple interconverting conformational states. Such intrinsically disordered proteins or protein segments are highly abundant across proteomes, and are involved in various effector functions.
Hampapathalu A Nagarajaram, Rakesh Trivedi   +1 more
exaly   +3 more sources

Intrinsically Disordered Proteins and Proteins With Intrinsically Disordered Regions in Neurodegenerative Diseases

Biophysical Reviews, 2022
Many different intrinsically disordered proteins and proteins with intrinsically disordered regions are associated with neurodegenerative diseases. These types of proteins including amyloid-β, tau, α-synuclein, CHCHD2, CHCHD10, and G-protein coupled receptors are increasingly becoming evaluated as potential drug targets in the pharmaceutical-based ...
Orkide Coşkuner-Weber, Vladimir Uversky
exaly   +5 more sources