Results 141 to 150 of about 5,123 (214)

Programming cellular condensates for living materials using an intrinsically disordered protein display platform. [PDF]

Proc Natl Acad Sci U S A
Chang R, Tu HX, Ma H, Joshi NS.
europepmc   +1 more source

Hidden Markov Models for detection of intrinsically disordered regions of proteins

openThe aim of this research is to build a collection of Hidden Markov Models (HMMs) that can accurately identify intrinsically disordered protein (IDP) domains as defined in the manually curated databases.
SKRYLNIK, ALINA
core  

Assessment of Missense Intolerant Regions (MIRs) in Intrinsically Disordered Proteins (IDPs)

Genes that are crucial for the function of an organism are depleted of disrupting variants in natural populations, whereas non-essential genes tolerate their accumulation. Next-generation sequencing (NGS) of the general population has enabled comprehensive coverage of the human genome, identifying single nucleotide variants (SNVs) at an impressive ...
openaire   +1 more source

Conformational dynamics and association of intrinsically disordered proteins (IDPs) using molecular dynamics simulations

Conformational dynamics and association of intrinsically disordered proteins (IDPs) using molecular dynamics simulations
No 2nd Integrative Structural Biology ...
openaire  

Hierarchical multi-timescale structural dynamics of the disordered N-terminal of p53. [PDF]

Nat Commun
Szöllősi D, Pratihar S, Mukhopadhyay D, Rout AK, Han M, Reddy GJ, Ebersberger N, Becker S, Nagy G, Rauscher S, Lee D, Klement R, Griesinger C, Grubmüller H.   +13 more
europepmc   +1 more source

Sequence-Dependent Conformational Landscapes of Intrinsically Disordered Proteins Reveal Asymmetric Chain Compaction. [PDF]

J Chem Theory Comput
Wang C, Zhang B.
europepmc   +1 more source

Reading Between the ABCs: Intrinsic Disorder and Evolutionary Dynamics of Non-Canonical Regions in ABC Transporters. [PDF]

Int J Mol Sci
Dinana IA, Kubota Y, Ito M.
europepmc   +1 more source

How Well Do Molecular Dynamics Force Fields Model Peptides: A Systematic Benchmark across Diverse Folding Behaviors. [PDF]

J Phys Chem B
Singh B, Martínez-Noa Y, Perez A.
europepmc   +1 more source

Sequence and length-scale dependent dynamics in biocondensates of highly charged disordered proteins. [PDF]

Commun Chem
Zhou H, Wu Z, Jiang L, Chen S, Wang ZG.
europepmc   +1 more source

Molecular origins of viscoelasticity in biomolecular condensates. [PDF]

J Chem Phys
Garcia PL, Joseph JA.
europepmc   +1 more source