Results 11 to 20 of about 2,551 (127)

A new method to quantify the human visual threshold from melanopsin sensitive ganglion cells

open access: yesFrontiers in Cellular Neuroscience, 2023
Traditional photoreceptors utilize the chromophore retinal to absorb light coupled with a unique opsin protein to specify receptor spectral sensitivity.
Jeff Rabin   +7 more
doaj   +1 more source

Localization of melatonin receptor 1 in mouse retina and its role in the circadian regulation of the electroretinogram and dopamine levels. [PDF]

open access: yesPLoS ONE, 2011
Melatonin modulates many important functions within the eye by interacting with a family of G-protein-coupled receptors that are negatively coupled with adenylate cyclase.
Anamika Sengupta   +6 more
doaj   +1 more source

Circuit mechanisms underlying embryonic retinal waves

open access: yeseLife, 2023
Spontaneous activity is a hallmark of developing neural systems. In the retina, spontaneous activity comes in the form of retinal waves, comprised of three stages persisting from embryonic day 16 (E16) to eye opening at postnatal day 14 (P14).
Christiane Voufo   +5 more
doaj   +1 more source

Melanopsin Retinal Ganglion Cells Regulate Cone Photoreceptor Lamination in the Mouse Retina

open access: yesCell Reports, 2018
Summary: Newborn neurons follow molecular cues to reach their final destination, but whether early life experience influences lamination remains largely unexplored.
Adele R. Tufford   +9 more
doaj   +1 more source

Burning the candle at both ends: Intraretinal signaling of intrinsically photosensitive retinal ganglion cells

open access: yesFrontiers in Cellular Neuroscience, 2023
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are photoreceptors located in the ganglion cell layer. They project to brain regions involved in predominately non-image-forming functions including entrainment of circadian rhythms, control of
Sushmitha Raja   +3 more
doaj   +1 more source

Dissociation of pupillary post-illumination responses from visual function in confirmed OPA1 c.983A>G and c.2708_ 2711delTTAG autosomal dominant optic atrophy.

open access: yesFrontiers in Neurology, 2015
Purpose: To test whether the melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs), as evaluated by examination of the pupillary light reflex (PLR), are preserved in genetically confirmed autosomal dominant optic atrophy ...
Claus eNissen   +6 more
doaj   +1 more source

Melanopsin ganglion cells are the most resistant retinal ganglion cell type to axonal injury in the rat retina.

open access: yesPLoS ONE, 2014
We report that the most common retinal ganglion cell type that remains after optic nerve transection is the M1 melanopsin ganglion cell. M1 ganglion cells are members of the intrinsically photosensitive retinal ganglion cell population that mediates non ...
Luis Pérez de Sevilla Müller   +3 more
doaj   +1 more source

Biophysical Variation within the M1 Type of Ganglion Cell Photoreceptor

open access: yesCell Reports, 2017
Summary: Intrinsically photosensitive retinal ganglion cells of the M1 type encode environmental irradiance for functions that include circadian and pupillary regulation.
Alan J. Emanuel   +2 more
doaj   +1 more source

Mood and behavior seasonality in glaucoma; assessing correlations between seasonality and structure and function of the retinal ganglion cells.

open access: yesPLoS ONE, 2020
AIM:In glaucoma, depression and disturbed sleep has been associated with degeneration of the intrinsically photosensitive retinal ganglion cells, that mediate non-image forming effects of light such as regulation of circadian rhythm, alertness and mood ...
Helle Østergaard Madsen   +4 more
doaj   +1 more source

Early alterations of neurovascular unit in the retina in mouse models of tauopathy

open access: yesActa Neuropathologica Communications, 2021
The retina, as the only visually accessible tissue in the central nervous system, has attracted significant attention for evaluating it as a biomarker for neurodegenerative diseases.
Fan Xia   +9 more
doaj   +1 more source

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