Functional Characterization of Argininosuccinate Lyase Gene Variants by Mini-Gene Splicing Assay
Frontiers in Genetics, 2019 ObjectiveArgininosuccinate lyase (ASL) gene mutations account for argininosuccinic aciduria (ASA). This study aimed to design a minigene construct of ASL gene in order to investigate the impact of variants on splicing.MethodsThe peripheral blood samples ...
Yanyun Wang +5 more
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A novel role for the 3' region of introns in pre-mRNA splicing of Saccharomyces cerevisiae. [PDF]
, 1987 Brian C. Rymond +2 more
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Kluyveromyces lactis maintains Saccharomyces cerevisiae intron-encoded splicing signals. [PDF]
, 1989 James O. Deshler, G P Larson, J J Rossi
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Phylogeny of conserved adenines in linkers of Group-I introns [PDF]
, 2009 We have analyzed the linkers in group-I introns, a characteristic region that is crucial to the folding and splicing process of the folded RNA, in seventy sequences spreading across r-RNA, t-RNA and organelle genes from various organisms including algae,
Chandrasekhar Kesavan, Natarajan Ganesan
core +1 more source
Construction of a yeast actin gene intron deletion mutant that is defective in splicing and leads to the accumulation of precursor RNA in transformed yeast cells. [PDF]
, 1982 Dieter Gallwitz
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Inhomogeneous DNA: conducting exons and insulating introns
, 2009 Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different.
A. A. Krokhin +7 more
core +2 more sources
The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
Cell, 2017 Kathryn E. Pendleton +6 more
semanticscholar +1 more source
Analysis of intron sequences reveals hallmarks of circular RNA biogenesis in animals.
Cell Reports, 2015 Andranik Ivanov +10 more
semanticscholar +1 more source
Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms
, 2010 The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel. Several hERG1 isoforms with different N- and C-terminal ends have been identified.
Gong, Qiuming +4 more
core
Intron length polymorphism of actin genes in different varieties of ukrainian selection flax
, 1970 A. С. Postovoitova +3 more
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