Results 151 to 160 of about 232,441 (272)
Molecular biology: No introns in insect globin genes [PDF]
, 1984 Athel Cornish‐Bowden
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Animal Models and Experimental Medicine, EarlyView.KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei +4 more
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CD8+ T cell memory is sustained in mice by hepatic stellate cells
Hepatology, EarlyView., 2022 HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen +4 more
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Self-splicing of a group II intron in yeast mitochondria: dependence on 5′ exon sequences. [PDF]
, 1987 Renske M. van der Veen +2 more
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Annals of Neurology, EarlyView.Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino +13 more
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TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
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Corrigendum: Novel Genomic and Evolutionary Perspective of Cyanobacterial tRNAs
Frontiers in Genetics, 2020 Tapan K. Mohanta +3 more
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Development of algorithms and software for classification of nucleotide sequences
Informatika, 2019 Coding and non-coding nucleotide sequences of the human reference genome have been investigated. Seven models of vectorization of nucleotide sequences based on mono-, bi-, trigram nucleotide frequencies, parameters of the category-position-frequency ...
V. R. Zakirava +4 more
doaj
Evidence that introns arose at proto-splice sites. [PDF]
, 1989 N. J. Dibb, Andrew J. Newman
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Brain Metabolic Features of FUS‐ALS: A 2‐[18F]FDG‐PET Study
Annals of Neurology, EarlyView.Objective We aimed at evaluating the brain metabolic features of fused in sarcoma amyotrophic lateral sclerosis (FUS‐ALS) compared with sporadic ALS (sALS), using 2‐[fluorine‐18] fluoro‐2‐deoxy‐D‐glucose positron emission tomography (2‐[18F]FDG‐PET). Methods We employed the 2‐sample t‐test model of SPM12, implemented in MATLAB, to compare 12 FUS‐ALS ...
Antonio Canosa +24 more
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