Results 11 to 20 of about 250,365 (285)
The insertion of a mitochondrial selfish element into the nuclear genome and its consequences
Ecology and Evolution, 2020 Homing endonucleases (HE) are enzymes capable of cutting DNA at highly specific target sequences, the repair of the generated double‐strand break resulting in the insertion of the HE‐encoding gene (“homing” mechanism).
Julien Y. Dutheil +4 more
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Systematic Identification and Functional Validation of New snoRNAs in Human Muscle Progenitors
Non-Coding RNA, 2021 Small non-coding RNAs (sncRNAs) represent an important class of regulatory RNAs involved in the regulation of transcription, RNA splicing or translation.
Baptiste Bogard +2 more
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Intron Mobility: Invasive introns [PDF]
Current Biology, 1994 The evidence that introns in fungal and plant organellar DNAs are mobile genetic elements has strengthened significantly; like Shaw's cockney heroine, Eliza Doolittle, they cannot help but betray their origins.
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Microbial Cell Factories, 2019 Background O-Methylated phenylpropanoids, which are generally present in small amounts in plants, have improved or distinct biological activities and pharmacological properties as opposed to their unmethylated counterparts.
Heqing Cui +6 more
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Applied Barcoding: The Practicalities of DNA Testing for Herbals
Plants, 2020 DNA barcoding is a widely accepted technique for the identification of plant materials, and its application to the authentication of commercial medicinal plants has attracted significant attention.
Caroline Howard +2 more
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RHD Genotypes in a Chinese Cohort of Pregnant Women
Frontiers in Genetics, 2021 RHD variants in D¯ Chinese pregnant women arose difficulties in management during pregnancy. Therefore, this study aims to precisely manage D¯ pregnant women by evaluating the spectrum of RHD mutations in D¯ pregnant women and getting insight into the ...
Jianjun Zhang +17 more
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mAbs, 2023 Introns are included in genes encoding therapeutic proteins for their well-documented function of boosting expression. However, mis-splicing of introns in recombinant immunoglobulin (IgG) heavy chain (HC) transcripts can produce amino acid sequence ...
Emma Kelsall +5 more
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Frontiers in Molecular Biosciences, 2021 An evolutionarily conserved feature of introns is their ability to enhance expression of genes that harbor them. Introns have been shown to regulate gene expression at the transcription and post-transcription level.
Katherine Dwyer +3 more
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An overview of RNA splicing and functioning of splicing factors in land plant chloroplasts
RNA Biology, 2022 RNA splicing refers to a process by which introns of a pre-mRNA are excised and the exons at both ends are joined together. Chloroplast introns are inherently self-splicing ribozymes, but over time, they have lost self-splicing ability due to the ...
Xuemei Wang +4 more
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Intronization, de-intronization and intron sliding are rare in Cryptococcus [PDF]
BMC Evolutionary Biology, 2009 Eukaryotic pre-mRNA gene transcripts are processed by the spliceosome to remove portions of the transcript, called spliceosomal introns. The spliceosome recognizes intron boundaries by the presence of sequence signals (motifs) contained in the actual transcript, thus sequence changes in the genome that affect existing splicing signals or create new ...
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