Results 21 to 30 of about 232,441 (272)

Introns as Gene Regulators: A Brick on the Accelerator

open access: yesFrontiers in Genetics, 2019
A picture is beginning to emerge from a variety of organisms that for a subset of genes, the most important sequences that regulate expression are situated not in the promoter but rather are located within introns in the first kilobase of transcribed ...
Alan B. Rose
doaj   +1 more source

Mitochondrial genomes and phylogenomic analysis of Ulva lactuca Linnaeus (Ulvophyceae, Chlorophyta)

open access: yesMitochondrial DNA. Part B. Resources, 2020
Two mitogenomes of Ulva lactuca Linnaeus, one from Florida, USA and another nearly complete mtDNA from Chile, had previously been sequenced. Here, the complete mitogenome of U. lactuca from Shantou, China was sequenced and compared with them.
Manman Liu   +4 more
doaj   +1 more source

The role of transposable elements in the evolution of non-mammalian vertebrates and invertebrates [PDF]

open access: yesGenome Biology 2010, 11:R59, 2010
Background: Transposable elements (TEs) have played an important role in the diversification and enrichment of mammalian transcriptomes through various mechanisms such as exonization and intronization (the birth of new exons/introns from previously intronic/exonic sequences, respectively), and insertion into first and last exons.
arxiv   +1 more source

Exons, introns and DNA thermodynamics [PDF]

open access: yesPhys. Rev. Lett. 94, 178101 (2005), 2004
The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis. We have analyzed the melting behavior of randomly selected human cDNA sequences obtained from the genomic DNA by removing all introns. A clear correspondence
arxiv   +1 more source

Identification of a dinucleotide signature that discriminates coding from non-coding long RNAs

open access: yesFrontiers in Genetics, 2014
To date, the main criterion by which long ncRNAs (lncRNAs) are discriminated from mRNAs is based on the capacity of the transcripts to encode a protein. However, it becomes important to identify non-ORF-based sequence characteristics that can be used to ...
Damien eUlveling   +3 more
doaj   +1 more source

Comparative Mitogenomic Analysis Reveals Intraspecific, Interspecific Variations and Genetic Diversity of Medical Fungus Ganoderma

open access: yesJournal of Fungi, 2022
Ganoderma species are widely distributed in the world with high diversity. Some species are considered to be pathogenic fungi while others are used as traditional medicine in Asia.
Qiang Li   +9 more
doaj   +1 more source

Use of a Fluorescent Aptamer RNA as an Exonic Sequence to Analyze Self-Splicing Ability of a Group I Intron from Structured RNAs

open access: yesBiology, 2016
Group I self-splicing intron constitutes an important class of functional RNA molecules that can promote chemical transformation. Although the fundamental mechanism of the auto-excision from its precursor RNA has been established, convenient assay ...
Airi Furukawa   +4 more
doaj   +1 more source

Intron Regions as Genetic Markers for Population Genetic Investigations of Opisthorchis viverrini sensu lato and Clonorchis sinensis

open access: yesAnimals, 2023
Opisthorchiasis and clonorchiasis are prevalent in Southeast and Far-East Asia, which are caused by the group 1 carcinogenic liver flukes Opisthorchis viverrini sensu lato and Clonorchis sinensis infection. There have been comprehensive investigations of
Chairat Tantrawatpan   +7 more
doaj   +1 more source

Inhomogeneous DNA: conducting exons and insulating introns [PDF]

open access: yesPhys. Rev. B 80 (2009) 085420, 2009
Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different. Taking into account long-range correlations among four basic nucleotides that form double-stranded DNA sequence, we calculate electron localization length for ...
arxiv   +1 more source

Whole genome sequencing reveals novel IGHMBP2 variant leading to unique cryptic splice‐site and Charcot‐Marie‐Tooth phenotype with early onset symptoms

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Rare variants (RV) in immunoglobulin mu‐binding protein 2 (IGHMBP2) [OMIM 600502] can cause an autosomal recessive type of Charcot‐Marie‐Tooth (CMT) disease [OMIM 616155], an inherited peripheral neuropathy.
Thomas A. Cassini   +9 more
doaj   +1 more source

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