Results 31 to 40 of about 317,196 (344)
Applied Barcoding: The Practicalities of DNA Testing for Herbals
Plants, 2020 DNA barcoding is a widely accepted technique for the identification of plant materials, and its application to the authentication of commercial medicinal plants has attracted significant attention.
Caroline Howard +2 more
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A unified mechanism for intron and exon definition and back-splicing
Nature, 2019 The molecular mechanisms of exon definition and back-splicing are fundamental unanswered questions in pre-mRNA splicing. Here we report cryo-electron microscopy structures of the yeast spliceosomal E complex assembled on introns, providing a view of the ...
Xueni Li +12 more
semanticscholar +1 more source
Novel Genomic and Evolutionary Perspective of Cyanobacterial tRNAs
Frontiers in Genetics, 2017 Transfer RNA (tRNA) plays a central role in protein synthesis and acts as an adaptor molecule between an mRNA and an amino acid. A tRNA has an L-shaped clover leaf-like structure and contains an acceptor arm, D-arm, D-loop, anti-codon arm, anti-codon ...
Tapan K. Mohanta +3 more
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Frontiers in Molecular Biosciences, 2021 An evolutionarily conserved feature of introns is their ability to enhance expression of genes that harbor them. Introns have been shown to regulate gene expression at the transcription and post-transcription level.
Katherine Dwyer +3 more
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Taxonomy of introns and the evolution of minor introns [PDF]
Nucleic Acids ResearchAbstract Classification of introns, which is crucial to understanding their evolution and splicing, has historically been binary and has resulted in the naming of major and minor introns that are spliced by their namesake spliceosome. However, a broad range of intron consensus sequences exist, leading us to here reclassify introns as ...
Anouk M Olthof +9 more
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The changing paradigm of intron retention: regulation, ramifications and recipes
Nucleic Acids Research, 2019 Intron retention (IR) is a form of alternative splicing that has long been neglected in mammalian systems although it has been studied for decades in non-mammalian species such as plants, fungi, insects and viruses.
Geoffray Monteuuis +4 more
semanticscholar +1 more source
Coevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic Life
Life, 2016 The origins of the components of genetic coding are examined in the present study. Genetic information arose from replicator induction by metabolite in accordance with the metabolic expansion law.
J. Tze-Fei Wong +4 more
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Veterinary Sciences, 2020 DNA methylation of different gene components, including different exons and introns, or different lengths of exons and introns is associated with differences in gene expression.
Xiao Wang, Haja N. Kadarmideen
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Gene prediction with a hidden Markov model and a new intron submodel
European Conference on Computational Biology, 2003 MOTIVATION The problem of finding the genes in eukaryotic DNA sequences by computational methods is still not satisfactorily solved. Gene finding programs have achieved relatively high accuracy on short genomic sequences but do not perform well on longer
M. Stanke, S. Waack
semanticscholar +1 more source
Intron exclusion and the mystery of intron loss [PDF]
FEBS Letters, 2006 Mechanisms for loss and gain of introns are elusive. Reported here is a new pattern of intron loss which features a random loss of a single intron in a multiple‐intron gene with its neighboring introns remained, which process is defined as intron exclusion.
openaire +3 more sources