Results 31 to 40 of about 397,235 (339)

Intron exclusion and the mystery of intron loss [PDF]

open access: yesFEBS Letters, 2006
Mechanisms for loss and gain of introns are elusive. Reported here is a new pattern of intron loss which features a random loss of a single intron in a multiple‐intron gene with its neighboring introns remained, which process is defined as intron exclusion.
openaire   +3 more sources

Intron-mediated enhancement is not limited to introns [PDF]

open access: yes, 2018
AbstractCertain introns strongly increase mRNA accumulation by a poorly understood mechanism known as Intron-Mediated Enhancement (IME). Introns that boost expression by IME have no effect when located upstream of or more than ~1 Kb downstream from the start of transcription.
Gallegos, Jenna E, Rose, Alan B
openaire   +1 more source

Region-Specific Network Analysis Reveals That Epigenetic Modifications Outside Transcriptional Start Sites Are Tightly Linked to mRNA

open access: yesIEEE Access, 2021
While most data analysis of epigenetic modifications has focused on the transcriptional start site proximal region (TPR), the non-TPR has received less attention.
Kun Yang, Jing Xu
doaj   +1 more source

Group II Intron Protein Localization and Insertion Sites Are Affected by Polyphosphate [PDF]

open access: yes, 2008
Mobile group II introns consist of a catalytic intron RNA and an intron-encoded protein with reverse transcriptase activity, which act together in a ribonucleoprotein particle to promote DNA integration during intron mobility.
Lambowitz, Alan M.   +5 more
core   +5 more sources

Intron or no intron: a matter for nuclear pore complexes [PDF]

open access: yesNucleus, 2015
Nuclear pore complexes (NPCs) have been shown to regulate distinct steps of the gene expression process, from transcription to mRNA export. In particular, mRNAs expressed from intron-containing genes are surveyed by a specific NPC-dependent quality control pathway ensuring that unspliced mRNAs are retained within the nucleus.
Benoit Palancade, Amandine Bonnet
openaire   +3 more sources

Introns as Gene Regulators: A Brick on the Accelerator

open access: yesFrontiers in Genetics, 2019
A picture is beginning to emerge from a variety of organisms that for a subset of genes, the most important sequences that regulate expression are situated not in the promoter but rather are located within introns in the first kilobase of transcribed ...
Alan B. Rose
doaj   +1 more source

Reliable and robust molecular sexing of the hen harrier (Circus cyaneus) using PCR-RFLP of the CHD1 gene [PDF]

open access: yes, 2013
The hen harrier (Circus cyaneus) is a bird of prey that is persecuted in the United Kingdom, and there is a need for a DNA-based individual identification and sexing system for the use in forensic investigations.
Henderson, A   +4 more
core   +1 more source

Intron Evolution in Saccharomycetaceae [PDF]

open access: yesGenome Biology and Evolution, 2014
Introns in protein-coding genes are very rare in hemiascomycetous yeast genomes. It has been suggested that these species have experienced extensive intron loss during their evolution from the postulated intron-rich fungal ancestor. However, no intron-devoidy east species have been identified and some of the introns remaining within the genomes of ...
Sam Griffiths-Jones   +3 more
openaire   +4 more sources

Mitochondrial genomes and phylogenomic analysis of Ulva lactuca Linnaeus (Ulvophyceae, Chlorophyta)

open access: yesMitochondrial DNA. Part B. Resources, 2020
Two mitogenomes of Ulva lactuca Linnaeus, one from Florida, USA and another nearly complete mtDNA from Chile, had previously been sequenced. Here, the complete mitogenome of U. lactuca from Shantou, China was sequenced and compared with them.
Manman Liu   +4 more
doaj   +1 more source

An orchestrated intron retention program in meiosis controls timely usage of transcripts during germ cell differentiation [PDF]

open access: yes, 2017
Global transcriptome reprogramming during sper-matogenesis ensures timely expression of factors in each phase of male germ cell differentiation. Sper-matocytes and spermatids require particularly exten-sive reprogramming of gene expression to switch from
Alberdi, Antonio J.   +9 more
core   +2 more sources

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