Results 51 to 60 of about 232,441 (272)
Contribution of Mobile Group II Introns to Sinorhizobium meliloti Genome Evolution
Frontiers in Microbiology, 2018 Mobile group II introns are ribozymes and retroelements that probably originate from bacteria. Sinorhizobium meliloti, the nitrogen-fixing endosymbiont of legumes of genus Medicago, harbors a large number of these retroelements.
Nicolás Toro +4 more
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FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Frontiers in Pediatrics, 2022 BackgroundThe precise genetic diagnosis of a sarcoglycanopathy or dystrophinopathy is sometimes extremely challenging, as pathogenic non-coding variants and/or complex structural variants do exist in DMD or sarcoglycan genes.
Zhiying Xie +16 more
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Selecting informative features of human gene exons
Журнал Белорусского государственного университета: Математика, информатика, 2019 Dimensionality reduction of the human gene exon feature space is considered with the aim of gene identification. To evaluate the performance of various feature selection algorithms, computational experiments were carried out using the examples of exons ...
Andrei V. Volkau +2 more
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Using profiles based on hydropathy properties to define essential regions for splicing [PDF]
International Journal of Biological Sciences (2009) 10 p, 2009 We define new profiles based on hydropathy properties and point out specific profiles for regions surrounding splice sites. We built a set T of flanking regions of genes with 1-3 introns from 21st and 22nd chromosomes. These genes contained 313 introns and 385 exons and were extracted from GenBank. They were used in order to define hydropathy profiles.
arxiv
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Frontiers in Genetics, 2014 A number of genome analyses and searches using programs that focus on the RNA-specific bulge-helix-bulge (BHB) motif have uncovered a wide variety of disrupted tRNA genes.
Akiko eSoma
doaj +1 more source
In search of lost introns [PDF]
arXiv, 2007 Many fundamental questions concerning the emergence and subsequent evolution of eukaryotic exon-intron organization are still unsettled. Genome-scale comparative studies, which can shed light on crucial aspects of eukaryotic evolution, require adequate computational tools.
arxiv
Skin calcium deposits in primary familial brain calcification: A novel potential biomarker
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder characterized by small vessel calcifications in the basal ganglia. PFBC is caused by pathogenic variants in different genes and its physiopathology is still largely unknown. Skin vascular calcifications have been detected in single PFBC cases, suggesting
Aron Emmi +8 more
wiley +1 more source
Frontiers in Genetics, 2019 At the end of introns, the polypyrimidine tract (Py) is often close to the 3′ AG in a consensus (Y)20NCAGgt in humans. Interestingly, we have found that they could also be separated by purine-rich elements including G tracts in thousands of human genes ...
Hai Nguyen, Hai Nguyen, Jiuyong Xie
doaj +1 more source