Results 131 to 140 of about 144,700 (293)

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Introns increase gene expression in Caenorhabditis elegans by a mechanism that must be at least partly different than in plants

Scientific Reports
The wide diversity of organisms in which introns stimulate gene expression suggests that this is an ancient phenomenon. However, the mechanisms through which introns boost expression remain poorly understood, and the degree the which the action of ...
Alan B. Rose, Aaron Baer, Isaac Shaker, J. Grey Monroe, Ian Korf, Lesilee S. Rose   +5 more
doaj   +1 more source

Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice

Advanced Science, EarlyView.
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang, Zhengting Chen, Pengxiang Bai, Biao Liu, Lingling Meng, Jian Zhang, Xu Li, Dao‐Xiu Zhou, Xuan Ma, Yu Zhao   +9 more
wiley   +1 more source

Bacterial group I introns [PDF]

, 2015
Introni grupe I su intervencijski sljedovi koji se nalaze unutar tRNA, rRNA i protein kodirajućih gena u bakterijama i bakteriofagima, te su također pronađeni u genima jezgre, kloroplasta i mitohondrija eukariota.
Vučetić, Adriana
core  

A Conserved DT2‐bZIP66‐NF‐YC4 Regulatory Module Confers Drought Tolerance in Rice and Arabidopsis

Advanced Science, EarlyView.
This study identifies a conserved tripartiteDT2–bZIP66–NF‐YC4 transcriptional module that enhances rice drought tolerance by activating stress‐responsive genes. This regulatory complex is functionally conserved across cereals and Arabidopsis, providing promising targets for engineering drought‐resilient crops. ABSTRACT Drought stress severely restricts
Jun Shen, Yuchen Li, Liang Zhang, Xiaosong Ma, Chenyin Peng, Chunting Yuan, Yu Wu, Kaiyu Zhao, Sheng Zhao, Jiazhuo Guo, Run Li, Ziqian Yan, Shule Ren, Yige Han, Xin Lin, Xinyue Li, Ming Li, Pingfang Yang, Shiyong Song   +18 more
wiley   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Differences between standard introns and protointrons.

, 2019
(A) Splice site and branchpoint sequences of protointrons are less constrained in sequence than the standard introns. Weblogos representing position-specific weight matrices of the 5’ ss, branch points, and 3’ ss of the standard introns (top) and the ...
Jason Talkish (7300940), Robert Shelansky (7300949), Manuel Ares Jr. (7300955), Haller Igel (57417), Lily Shiue (10734), John Paul Donohue (7300952), Sol Katzman (140070), Elizabeth M. Munding (7300946), Rhonda J. Perriman (7300943)   +8 more
core   +1 more source

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li, Guiying Shi, Jiaming Tang, Yiying Huang, Jie Wang, Xuepei Lei, Lin Bai   +6 more
wiley   +1 more source

Group I Introns Found inChlorellaViruses: Biological Implications

, 1998
More than 80 group I introns were detected and characterized inChlorellaviruses isolated from various locations in Japan; the overall average frequency of viruses containing the group I intron was 8.0%. Although most of these introns were inserted in the
Fujie, Makoto, Yamada, Takashi, Nomura, Nobuhiko, Kimura, Yoshiki, Nishida, Kensho, Suzuki, Satoshi   +5 more
core   +1 more source

HybSuite: An integrated pipeline for hybrid capture phylogenomics from reads to trees

Applications in Plant Sciences, EarlyView.
Abstract Premise Hybrid capture sequencing (Hyb‐Seq) is a widely used approach in phylogenomics, providing efficient access to targeted genomic regions. However, deriving high‐quality phylogenetic trees from raw sequencing reads requires extensive bioinformatics processing, which increases complexity, the risk of errors, and challenges in file ...
Yu‐Xuan Liu, Zi‐Jia Lu, Wyckliffe Omondi Omollo, Meng‐Meng Wang, Li‐Guo Zhang, Tao Xiong, Xue‐Qin Wang, Yi‐Ying Wang, Miao Sun   +8 more
wiley   +1 more source