From apex to base: Uncovering spatial metabolic adaptation in Antarctic mosses
Antarctic mosses survive extreme cold, desiccation, UV exposure, and oxidative stress. We analyzed three species by separating apical, middle, and basal zones. Each zone showed distinct metabolite patterns and biological roles, revealing spatial metabolic specialization. The results suggest that whole‐plant survival depends on coordinated contributions
Fatima Tuz Zahra +7 more
wiley +1 more source
Junction, what's your function? Mapping the exon junction complex in Arabidopsis. [PDF]
Lohani N, Singla-Rastogi M.
europepmc +1 more source
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang +23 more
wiley +1 more source
From water to land: evolution of tRNA gene repertoires in photosynthetic organisms. [PDF]
Hummel G, Pflieger D, Berr A, Drouard L.
europepmc +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Intronic RNA of yeast RPL22 paralogs acts as an allosteric switch. [PDF]
Abrhámová K +4 more
europepmc +1 more source
Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang +10 more
wiley +1 more source
Splicing dependency between EIF4G2 introns is mediated by exon definition and relies on a downstream splicing event. [PDF]
Pelletier ML +8 more
europepmc +1 more source
A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin
The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You +13 more
wiley +1 more source
Assembly and comparative analysis of the complete mitochondrial genomes of five <i>Thaxterogaster</i> species (<i>Cortinariaceae</i>, <i>Basidiomycota</i>): Insights into mitochondrial genome evolution and intrageneric phylogenetic relationships. [PDF]
Ou LY, Xie ML, Li Y, Li CT.
europepmc +1 more source

