Results 11 to 20 of about 292,600 (397)
Organellar Introns in Fungi, Algae, and Plants
Introns are ubiquitous in eukaryotic genomes and have long been considered as ‘junk RNA’ but the huge energy expenditure in their transcription, removal, and degradation indicate that they may have functional significance and can offer evolutionary ...
Jigeesha Mukhopadhyay, Georg Hausner
doaj +2 more sources
Stability domains of actin genes and genomic evolution [PDF]
In eukaryotic genes the protein coding sequence is split into several fragments, the exons, separated by non-coding DNA stretches, the introns. Prokaryotes do not have introns in their genome.
A. Dkhissi+9 more
core +2 more sources
Exons, introns and DNA thermodynamics [PDF]
The genes of eukaryotes are characterized by protein coding fragments, the exons, interrupted by introns, i.e. stretches of DNA which do not carry any useful information for the protein synthesis.
A. Stoltzfus+11 more
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Inhomogeneous DNA: conducting exons and insulating introns [PDF]
Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different.
A. A. Krokhin+7 more
core +3 more sources
Introns increase gene expression in Caenorhabditis elegans by a mechanism that must be at least partly different than in plants [PDF]
The wide diversity of organisms in which introns stimulate gene expression suggests that this is an ancient phenomenon. However, the mechanisms through which introns boost expression remain poorly understood, and the degree the which the action of ...
Alan B. Rose+5 more
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Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome [PDF]
Background: Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human transcriptome and the mouse transcriptome.
Ast, Gil+5 more
core +4 more sources
Plant intron sequences: evidence for distinct groups of introns [PDF]
In vivo and in vitro RNA splicing experiments have demonstrated that the intron splicing machineries are not interchangeable in all organisms. These differences have prevented the efficient in vivo expression of monocot genes containing introns in dicot plants and the in vitro excision of some plant introns in HeLa cell in vitro splicing extracts.
Brian A. Hanley, Mary A. Schuler
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Keep Me Around: Intron Retention Detection and Analysis [PDF]
We present a tool, keep me around (kma), a suite of python scripts and an R package that finds retained introns in RNA-Seq experiments and incorporates biological replicates to reduce the number of false positives when detecting retention events.
Conboy, John G.+2 more
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Phase distribution of spliceosomal introns: implications for intron origin [PDF]
Abstract Background The origin of spliceosomal introns is the central subject of the introns-early versus introns-late debate. The distribution of intron phases is non-uniform, with an excess of phase-0 introns. Introns-early explains this by speculating that a fraction of present-day introns were present between ...
Naoya Kenmochi+2 more
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Amino acid transporters (AATs) play a crucial role in facilitating the movement of amino acids across cellular membranes, which is vital for the growth and development of plants.
Itishree Nayak+13 more
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