Results 31 to 40 of about 292,600 (397)
Premise of the study: Using sequence data generated via target enrichment for phylogenetics requires reassembly of high-throughput sequence reads into loci, presenting a number of bioinformatics challenges.
Matthew G. Johnson+7 more
semanticscholar +1 more source
Introns as Gene Regulators: A Brick on the Accelerator
A picture is beginning to emerge from a variety of organisms that for a subset of genes, the most important sequences that regulate expression are situated not in the promoter but rather are located within introns in the first kilobase of transcribed ...
A. Rose
semanticscholar +1 more source
Animal, Fungi, and Plant Genome Sequences Harbor Different Non-Canonical Splice Sites
Most protein-encoding genes in eukaryotes contain introns, which are interwoven with exons. Introns need to be removed from initial transcripts in order to generate the final messenger RNA (mRNA), which can be translated into an amino acid sequence ...
Katharina Frey, Boas Pucker
doaj +1 more source
Splice and Dice: Intronic microRNAs, Splicing and Cancer
Introns span only a quarter of the human genome, yet they host around 60% of all known microRNAs. Emerging evidence indicates the adaptive advantage of microRNAs residing within introns is attributed to their complex co-regulation with transcription and ...
Alex C. H. Wong, John E. J. Rasko
doaj +1 more source
Intron Mobility: Invasive introns [PDF]
The evidence that introns in fungal and plant organellar DNAs are mobile genetic elements has strengthened significantly; like Shaw's cockney heroine, Eliza Doolittle, they cannot help but betray their origins.
openaire +3 more sources
Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3 [PDF]
Background: Alternative splicing (AS) of maturing mRNA can generate structurally and functionally distinct transcripts from the same gene. Recent bioinformatic analyses of available genome databases inferred a positive correlation between intron length ...
A Marchler-Bauer+100 more
core +5 more sources
Introns interrupt the continuity of many eukaryal genes, and therefore their removal by splicing is a crucial step in gene expression. Interestingly, even within Eukarya there are at least four splicing mechanisms.
Abelson, John+2 more
core +1 more source
Parenteau et al. (2019) and Morgan et al. (2019) showed that a subset of introns can work as non-coding RNAs that trap the spliceosome and decrease global splicing upon nutrient depletion in yeast, providing a new example of the functionality of introns, molecules that were previously assumed to be useless.
Sebastian Kadener, Michela Zaffagni
openaire +3 more sources
Fungal complexes are often composed of morphologically nearly indistinguishable species with high genetic similarity. However, despite their close relationship, they can exhibit distinct phenotypic differences in pathogenicity and production of ...
Joanna Wyrębek+7 more
doaj +1 more source
The current article focuses on the morphological and molecular characterization of the often inconspicuous genus Amicula. This recently erected genus from brackish and marine sediments was monotypic but here we describe two new tropical species: Amicula ...
Romain Gastineau+13 more
doaj +1 more source