Results 41 to 50 of about 304,363 (385)
BMC Genomics, 2019 Mutations in minor spliceosome components such as U12 snRNA (cerebellar ataxia) and U4atac snRNA (microcephalic osteodysplastic primordial dwarfism type 1 (MOPD1)) result in tissue-specific symptoms.
Anouk M Olthof +2 more
semanticscholar +1 more source
Evidence of widespread degradation of gene control regions in hominid genomes [PDF]
, 2005 Although sequences containing regulatory elements located close to protein-coding genes are often only weakly conserved during evolution, comparisons of rodent genomes have implied that these sequences are subject to some selective constraints ...
Eyre-Walker, Adam +2 more
core +3 more sources
Complete mitogenome of the streptophyte green alga Coleochaete scutata (Coleochaetophyceae)
Mitochondrial DNA. Part B. Resources, 2019 We have sequenced the mitogenome of Coleochaete scutata strain SAG 110.80M. This mitogenome is the largest among the streptophyte green algae examined to date.
Monique Turmel +2 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionMany members of the Ophiostomatales are of economic importance as they are bark-beetle associates and causative agents for blue stain on timber and in some instances contribute towards tree mortality.
Jigeesha Mukhopadhyay +2 more
doaj +1 more source
Most human introns are recognized via multiple and tissue-specific branchpoints
Genes & Development, 2018 Pineda and Bradley demonstrate that almost all human introns contain multiple branchpoints. Approximately three-quarters of constitutive introns exhibit tissue-specific branchpoint usage.
Jose Mario Bello Pineda, R. Bradley
semanticscholar +1 more source
Improved ontology for eukaryotic single-exon coding sequences in biological databases [PDF]
, 2018 Indexación: Scopus.Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term 'single-exon
Clausen, P. +4 more
core +2 more sources
Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics. [PDF]
, 2020 As sequencing read length has increased, researchers have quickly adopted longer reads for their experiments. Here, we examine 14 pathogen or host-pathogen differential gene expression data sets to assess whether using longer reads is warranted.
Bruno, Vincent M +9 more
core +2 more sources
tRNA introns: Presence, processing, and purpose
Wiley Interdisciplinary Reviews - RNA, 2019 The presence of introns in both protein‐coding and noncoding RNA transcripts is a fascinating phenomenon. It seems counterintuitive that an organism would devote precious time and energy to removing a nucleic acid sequence that will not be present in the
Casey A. Schmidt, A. Matera
semanticscholar +1 more source
Detained introns are a novel, widespread class of post-transcriptionally spliced introns
Genes & Development, 2015 Deep sequencing of embryonic stem cell RNA revealed many specific internal introns that are significantly more abundant than the other introns within polyadenylated transcripts. Boutz et al. identified thousands of these “detained” introns (DIs) in human
P. Boutz, A. Bhutkar, P. Sharp
semanticscholar +1 more source
Nucleic Acids Research, 1987 The sequence information for the splicing process of introns is found in the consensus sequences at the two splice sites. For long introns, of 300 or more nucleotides, the middle regions may provide additional specificity for splicing which can be investigated by defining an adequate quantitative parameter.
D G, Arquès, C J, Michel
openaire +3 more sources