Results 41 to 50 of about 132,973 (294)
Methods and Protocols, 2022 Intron evolution may be readily imaged through the combined use of the “dot plot” function of the NCBI BLAST, aligning two sequences at a time, and the Vertebrate “Multiz” alignment and conservation tool of the UCSC Genome Browser. With the NCBI BLAST, an ideal alignment of two highly conserved sequences generates a diagonal straight line in the plot ...
Maria Antonietta Panaro +4 more
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Identification of an Exceptionally Long Intron in the
mSphere, 2018 The unfolded protein response (UPR) in the endoplasmic reticulum (ER) is well conserved in eukaryotes from metazoa to yeast. The transcription factor HAC1 is a major regulator of the UPR in many eukaryotes. Deleting HAC1 in the yeast Candida parapsilosis
Elise Iracane +4 more
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Nucleic Acids Research, 1987 The sequence information for the splicing process of introns is found in the consensus sequences at the two splice sites. For long introns, of 300 or more nucleotides, the middle regions may provide additional specificity for splicing which can be investigated by defining an adequate quantitative parameter.
Christian J. Michel, Didier Arquès
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Intron definition in splicing of small Drosophila introns. [PDF]
Molecular and Cellular Biology, 1994 Approximately half of the introns in Drosophila melanogaster are too small to function in a vertebrate and often lack the pyrimidine tract associated with vertebrate 3' splice sites. Here, we report the splicing and spliceosome assembly properties of two such introns: one with a pyrimidine-poor 3' splice site and one with a pyrimidine-rich 3' splice ...
M Talerico, Susan M. Berget
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Complete mitogenome of the streptophyte green alga Coleochaete scutata (Coleochaetophyceae)
Mitochondrial DNA. Part B. Resources, 2019 We have sequenced the mitogenome of Coleochaete scutata strain SAG 110.80M. This mitogenome is the largest among the streptophyte green algae examined to date.
Monique Turmel +2 more
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Analysis of intron sequence features associated with transcriptional regulation in human genes. [PDF]
PLoS ONE, 2012 Although some preliminary work has revealed the potential transcriptional regulatory function of the introns in eukaryotes, additional evidences are needed to support this conjecture.
Huimin Li, Dan Chen, Jing Zhang
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Order of removal of conventional and nonconventional introns from nuclear transcripts of Euglena gracilis. [PDF]
PLoS Genetics, 2018 Nuclear genes of euglenids and marine diplonemids harbor atypical, nonconventional introns which are not observed in the genomes of other eukaryotes. Nonconventional introns do not have the conserved borders characteristic for spliceosomal introns or the
Natalia Gumińska +3 more
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A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
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Organellar Introns in Fungi, Algae, and Plants
Cells, 2021 Introns are ubiquitous in eukaryotic genomes and have long been considered as ‘junk RNA’ but the huge energy expenditure in their transcription, removal, and degradation indicate that they may have functional significance and can offer evolutionary ...
Jigeesha Mukhopadhyay, Georg Hausner
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FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
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