Results 71 to 80 of about 209,653 (293)

Distribution of introns in fungal histone genes. [PDF]

open access: yesPLoS ONE, 2011
Saccharomycotina and Taphrinomycotina lack intron in their histone genes, except for an intron in one of histone H4 genes of Yarrowia lipolytica. On the other hand, Basidiomycota and Perizomycotina have introns in their histone genes.
Choong-Soo Yun, Hiromi Nishida
doaj   +1 more source

Complex evolutionary dynamics of massively expanded chemosensory receptor families in an extreme generalist chelicerate herbivore [PDF]

open access: yes, 2016
While mechanisms to detoxify plant produced, anti-herbivore compounds have been associated with plant host use by herbivores, less is known about the role of chemosensory perception in their life histories.
Bajda-Wybouw, Sabina   +10 more
core   +4 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The origin of introns and their role in eukaryogenesis: a compromise solution to the introns-early versus introns-late debate?

open access: yesBiology Direct, 2006
Background Ever since the discovery of 'genes in pieces' and mRNA splicing in eukaryotes, origin and evolution of spliceosomal introns have been considered within the conceptual framework of the 'introns early' versus 'introns late' debate.
Koonin Eugene V
doaj   +1 more source

InTRONs in Biotech [PDF]

open access: yesMolecular Biotechnology, 2011
Eukaryotic gene expression relies on several complex molecular machineries that act in a highly coordinated fashion. These machineries govern all the different steps of mRNA maturation, from gene transcription and pre-mRNA processing in the nucleus to the export of the mRNA to the cytoplasm and its translation.
Skoko, Natasa   +3 more
openaire   +2 more sources

Genomic organization of nucleolin gene in carp fish: Evidence for several genes [PDF]

open access: yes, 2006
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200017&lng=es&nrm=isoThe protein nucleolin, functionally involved in the main steps of ribosome biogenesis, is codified by a single copy gene in mammals.
Alvarez, Marco   +5 more
core   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A new reference genome assembly for the microcrustacean Daphnia pulex [PDF]

open access: yes, 2017
Comparing genomes of closely related genotypes from populations with distinct demographic histories can help reveal the impact of effective population size on genome evolution. For this purpose, we present a high quality genome assembly of Daphnia pulex (
Ackerman, Matthew S   +12 more
core   +3 more sources

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Intronic MicroRNA (miRNA) [PDF]

open access: yesBioMed Research International, 2006
Nearly 97% of the human genome is composed of noncoding DNA, which varies from one species to another. Changes in these sequences often manifest themselves in clinical and circumstantial malfunction. Numerous genes in these non‐protein‐coding regions encode microRNAs, which are responsible for RNA‐mediated gene silencing through RNA interference (RNAi)‐
Lin, Shi-Lung   +2 more
openaire   +2 more sources

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