Results 71 to 80 of about 292,600 (397)
Complete mitogenome of the streptophyte green alga Coleochaete scutata (Coleochaetophyceae)
Mitochondrial DNA. Part B. Resources, 2019 We have sequenced the mitogenome of Coleochaete scutata strain SAG 110.80M. This mitogenome is the largest among the streptophyte green algae examined to date.
Monique Turmel +2 more
doaj +1 more source
Mammalian Introns: When the Junk Generates Molecular Diversity
International Journal of Molecular Sciences, 2015 Introns represent almost half of the human genome, yet their vast majority is eliminated from eukaryotic transcripts through RNA splicing. Nevertheless, they feature key elements and functions that deserve further interest.
F. Hubé, C. Francastel
semanticscholar +1 more source
Frontiers in Microbiology, 2019 Ciliated protists (ciliates) are widely used for investigating evolution, mostly due to their successful radiation after their early evolutionary branching.
Bo Pan +8 more
doaj +1 more source
Analysis of intron sequence features associated with transcriptional regulation in human genes. [PDF]
PLoS ONE, 2012 Although some preliminary work has revealed the potential transcriptional regulatory function of the introns in eukaryotes, additional evidences are needed to support this conjecture.
Huimin Li, Dan Chen, Jing Zhang
doaj +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq
eLife, 2017 R-loops are features of chromatin consisting of a strand of DNA hybridized to RNA, as well as the expelled complementary DNA strand. R-loops are enriched at promoters where they have recently been shown to have important roles in modifying gene ...
Jason G Dumelie, Samie R Jaffrey
doaj +1 more source
Homing endonucleases from mobile group I introns: discovery to genome engineering
Mobile DNA, 2014 Homing endonucleases are highly specific DNA cleaving enzymes that are encoded within genomes of all forms of microbial life including phage and eukaryotic organelles. These proteins drive the mobility and persistence of their own reading frames.
B. Stoddard
semanticscholar +1 more source
Rescue of splicing-mediated intron loss maximizes expression in lentiviral vectors containing the human ubiquitin C promoter. [PDF]
, 2014 Lentiviral vectors almost universally use heterologous internal promoters to express transgenes. One of the most commonly used promoter fragments is a 1.2-kb sequence from the human ubiquitin C (UBC) gene, encompassing the promoter, some enhancers, first
Cooper, Aaron R +3 more
core +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Dynamics of genomic innovation in the unicellular ancestry of animals
eLife, 2017 Which genomic innovations underpinned the origin of multicellular animals is still an open debate. Here, we investigate this question by reconstructing the genome architecture and gene family diversity of ancestral premetazoans, aiming to date the ...
Xavier Grau-Bové +6 more
doaj +1 more source