Results 91 to 100 of about 119,386 (290)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Replacement Of The Interocclusal Space Lost After Preparatıon Wıth An Orthodontıc Applıcatıon
Turkish Journal of Orthodontics, 1988 Interocclusal space achieved by the preparation of the teeth for the fixed prosthetic restorations could be lost with the extrusion of those teeth when a considerable elapse of time happened to be between the preparation of the teeth and the cementation ...
Hakan N. İşcan +2 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Management of a rare combination of dental trauma: A case report
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2007 The occurrence of combined injury of intrusion, avulsion and lateral luxation is rare and the mechanism responsible for this is intriguing. This case report describes such a combined injury and its management.
Suprabha B, Mogra S
doaj
Comparative Evaluation of Intrusion with Different Techniques
Turkish Journal of Orthodontics, 2006 The aim of this study was to compare the effectiveness of two fixed appliance techniques, which are commonly used for correction of a deep overbite. The study comprised of 38 patients (19 boys and 19 girls) in the treatment group with deep overbite (+4mm)
Mustafa Erkan +2 more
doaj +1 more source
An Improved Model for Alleviating Layer Seven Distributed Denial of Service Intrusion on Webserver [PDF]
, 2019 Modupe Odusami +5 more
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Journal of Pharmacy and Bioallied SciencesAim and Objective: This study aimed to compare the amount of maxillary incisor intrusion and root resorption using three methods: mini-implants, utility arches, and Connecticut intrusion arches.
Shilpa Vinu +5 more
doaj +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Composition of Hybrid Deep Learning Model and Feature Optimization for Intrusion Detection System [PDF]
, 2023 Azriel Henry +7 more
openalex +1 more source