Results 131 to 140 of about 384 (242)

Mechanistic Diversity in Photoexcited Radical Redox Chemistry: A Critical Evaluation

Angewandte Chemie International Edition, EarlyView.
Many high‐profile examples of photoredox catalysis are proposed to proceed via excitation of an open‐shell intermediate form of the catalyst. However, there is much debate over whether such mechanisms are realistic and, if so, exactly how they can occur.
Samuel J. Horsewill, Ryan Phelps, Joshua P. Barham, Daniel J. Scott   +3 more
wiley   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Nature Relatedness as an Orientation in Moral Psychology. [PDF]

Integr Psychol Behav Sci
Janhonen J, Kähönen J, Salmi I.
europepmc   +1 more source

The Problem of Purity in Moral Psychology. [PDF]

Pers Soc Psychol Rev, 2023
Gray K, DiMaggio N, Schein C, Kachanoff F.   +3 more
europepmc   +1 more source

Coherence‐Gated Wrapped‐Phase InSAR With Matrix‐Based Uncertainty Diagnostics for Burial‐Mound Hotspot Ranking (Sicily, Italy)

Archaeological Prospection, EarlyView.
ABSTRACT Burial mounds are key elements of Mediterranean funerary landscapes, but in intensively cultivated coastal plains their low‐relief expression is easily obscured by ploughing, levelling and rapidly changing surface conditions, making single‐date observations unreliable.
Salvatore Polverino, Hourakhsh Ahmadnia, Rokhsaneh Rahbarianyazd Ahmadnia   +2 more
wiley   +1 more source

Inspecting the factors of individualizing and binding moral value orientation in the Moral Foundations Questionnaire-2 for validation-a re-analysis of data from pre-service teachers in Ghana. [PDF]

Front Psychol
Wild S, Fobi D, Möhring M.
europepmc   +1 more source

COVID-19-Pandemie — ethische und ökonomische Herausforderungen für ein gelingendes Krisenmanagement. [PDF]

Wirtschaftsdienst, 2021
Biller-Andorno N, Kapitza T.
europepmc   +1 more source

Inferring Rheumatoid Arthritis Disease Activity Status From the Electronic Health Records Across Health Systems

Arthritis &Rheumatology, EarlyView.
Objective Disease activity plays a central role in rheumatoid arthritis (RA) clinical studies. The inconsistent availability of data on disease activity in real‐world electronic health records (EHRs) data has limited the ability to generate real‐world evidence (RWE).
David Cheng, Xuan Wang, Gregory C. McDermott, Jennifer S. Hanberg, Zoe Love, Katherine Zhong, Mary Jeffway, Jue Hou, Vidul Panickan, Rahul Sangar, Ying Qi, Connor Melley, Lauren Costa, Dakota Feil, Rachael Matty, Dana Weisenfeld, Abisayo Animashaun, Aimee Schreiner, Sara Morini, Lauren Rusnak, Andrew Cagan, Misti Paudel, J. Michael Gaziano, Brian Sauer, Michael Weinblatt, Joshua Baker, Bryant England, Yuk‐Lam Ho, Kelly Cho, Paul Monach, Grant W. Cannon, Nancy Shadick, Ted R. Mikuls, Tianxi Cai, Katherine P. Liao   +34 more
wiley   +1 more source

Semantic Foundations of Reductive Reasoning. [PDF]

Topoi (Dordr)
Gheorghiu AV, Pym DJ.
europepmc   +1 more source

If You're a Rawlsian, How Come You're So Close to Utilitarianism and Intuitionism? A Critique of Daniels's Accountability for Reasonableness. [PDF]

Health Care Anal, 2018
Badano G.
europepmc   +1 more source