Results 81 to 90 of about 426,018 (280)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

On odd powers of nonnegative polynomials that are not sums of squares

Forum of Mathematics, Sigma
We initiate a systematic study of nonnegative polynomials P such that $P^k$ is not a sum of squares for any odd $k\geq 1$ , calling such P stubborn. We develop a new invariant of a real isolated zero of a nonnegative polynomial in the plane,
Grigoriy Blekherman, Khazhgali Kozhasov, Bruce Reznick   +2 more
doaj   +1 more source

Robust Image Hashing Using Radon Transform and Invariant Features [PDF]

Radioengineering, 2016
A robust image hashing method based on radon transform and invariant features is proposed for image authentication, image retrieval, and image detection. Specifically, an input image is firstly converted into a counterpart with a normalized size.
Y.L. Liu, G.J. Xin, Y. Xiao
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

An Invariant Geometric Feature for Inter-Subject Lumbar Curve Alignment to Detect Spondylolisthesis

IEEE Access
Spondylolisthesis classification commonly relies on the shift distance (SD) feature. This feature measures the displacement between vertebrae but is sensitive to variations in size and rotational alignment of the vertebrae.
Podchara Klinwichit, Watcharaphong Yookwan, Athita Onuean, Paramate Horkaew, Sornsupha Limchareon, Jun-Su Jang, Suwanna Rasmequan, Krisana Chinnasarn   +7 more
doaj   +1 more source

General Helices of AW(k)-Type in the Lie Group

Journal of Applied Mathematics, 2012
We study curves of AW(k)-type in the Lie group G with a bi-invariant metric. Also, we characterize general helices in terms of AW(k)-type curve in the Lie group G.
Dae Won Yoon
doaj   +1 more source

Geometric Invariant Curve and Surface Normalization

, 2006
In this work, a geometric invariant curve and surface normalization method is presented. Translation, scale and shear are normalized by Principal Component Analysis (PCA) whitening. Independent Component Analysis (ICA) and the third order moments are then employed for rotation and reflection normalization.
Sait Sener, Mustafa Unel
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source