Results 101 to 110 of about 546,512 (289)
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
We study the well-known generalised version of the nonlinear Cahn–Hilliard evolution equation, supplemented with periodic boundary conditions. We study local bifurcations in the vicinity of spatially homogeneous equilibrium states.
A.N. Kulikov, D.A. Kulikov
doaj +1 more source
Reductions and conservation laws for BBM and modified BBM equations
In this paper, the classical Lie theory is applied to study the Benjamin-Bona-Mahony (BBM) and modified Benjamin-Bona-Mahony equations (MBBM) to obtain their symmetries, invariant solutions, symmetry reductions and differential invariants. By observation
Khorshidi Maryam +3 more
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Invariant Subspace and Classification of Soliton Solutions of the Coupled Nonlinear Fokas-Liu System
In this work, the coupled nonlinear Fokas-Liu system which is a special type of KdV equation is studied using the invariant subspace method (ISM). The method determines an invariant subspace and construct the exact solutions of the nonlinear partial ...
Aliyu Isa Aliyu +3 more
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
The Liapunov Center Theorem for a Class of Equivariant Hamiltonian Systems
We consider the existence of the periodic solutions in the neighbourhood of equilibria for 𝐶∞ equivariant Hamiltonian vector fields. If the equivariant symmetry 𝑆 acts antisymplectically and 𝑆2=𝐼, we prove that generically purely imaginary eigenvalues ...
Jia Li, Yanling Shi
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Lorentz invariant vacuum solutions in general relativity [PDF]
5 ...
openaire +3 more sources
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
INVARIANT FUNDAMENTAL SOLUTION OF THE WAVE OPERATOR
We present a method for determining a fundamental solution of the wave operator \(\square_ n=\partial^ 2/\partial t^ 2- \sum^{n}_{j=1}\partial^ 2/\partial x^ 2_ j\) for an arbitrary \(n\geq 1\) which, as we think, is simpler than other methods used up to now.
Szmydt, Zofia, Ziemian, Bogdan
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