Results 111 to 120 of about 7,793,267 (329)

F(R) Gravity’s Rainbow and Its Einstein Counterpart

open access: yesAdvances in High Energy Physics, 2016
Motivated by UV completion of general relativity with a modification of a geometry at high energy scale, it is expected to have an energy dependent geometry.
S. H. Hendi   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Invariance properties of the microstrain wave equation arising in microstructured solids

open access: yesResults in Physics
The Lie group method stands as a significant, powerful, and straightforward mathematical tool for discovering precise invariant solutions and traveling wave solutions in prevalent nonlinear evolution equations across engineering, applied mathematics, and
Muhammad Usman   +3 more
doaj   +1 more source

Forward Euler Solutions and Weakly Invariant Time-Delayed Systems

open access: yesAbstract and Applied Analysis, 2012
This paper presents a necessary and sufficient condition for the weak invariance property of a time-delayed system parametrized by a differential inclusion.
Norma L. Ortiz-Robinson   +1 more
doaj   +1 more source

Lorentz invariant vacuum solutions in general relativity [PDF]

open access: yesProceedings of the Steklov Institute of Mathematics, 2015
5 ...
openaire   +3 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

INVARIANT FUNDAMENTAL SOLUTION OF THE WAVE OPERATOR

open access: yesDemonstratio Mathematica, 1986
We present a method for determining a fundamental solution of the wave operator \(\square_ n=\partial^ 2/\partial t^ 2- \sum^{n}_{j=1}\partial^ 2/\partial x^ 2_ j\) for an arbitrary \(n\geq 1\) which, as we think, is simpler than other methods used up to now.
Szmydt, Zofia, Ziemian, Bogdan
openaire   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Existence, stability and the number of two-dimensional invariant manifolds for the convective Cahn–Hilliard equation

open access: yesPartial Differential Equations in Applied Mathematics
We study the well-known generalised version of the nonlinear Cahn–Hilliard evolution equation, supplemented with periodic boundary conditions. We study local bifurcations in the vicinity of spatially homogeneous equilibrium states.
A.N. Kulikov, D.A. Kulikov
doaj   +1 more source

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