Results 101 to 110 of about 970,391 (247)
Infectio, 2006 Bergeyella zoohelcum es un patógeno zoonótico principalmente asociado a mordeduras causadas por perros o gatos y es el único representante del género Bergeyella. En este estudio se reporta el aislamiento de B. zoohelcum de un neonato con bacteriemia. Las
PEDRO MARTÍNEZ, SALIM MÁTTAR
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Registros recientes delgasterópodo exótico Rapana venosa (Valenciennes, 1846) a lo largode la línea costera Argentina: ¿Está progresandolainvasiónhaciaelsur? [PDF]
, 2014 Se presentan los registros más recientes de R. venosa a lo largo de la línea costera de Argentina (2010-2013), incluyendo el hallazgo de un individuo en la albufera Mar Chiquita (200 km al sur del Río de la Plata).
Bruno, Luis Ignacio +1 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Preliminary study of the problems associated to the invasion of the yellow-legged hornet ("Vespa velutina" Lepeletier, 1836) in Galicia (Spain) [PDF]
, 2016 [Resumen] En el año 2004 se obtuvo el primer registro de avispa asiática (Vespa velutina Lepeletier, 1836) en Europa, concretamente en Francia, teniéndose constancia de su presencia en Galicia desde el año 2013.
Outón Cacheiro, Leticia
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Estudio de la variabilidad genética, factores de virulencia y mecanismos de invasión del epitelio respiratorio humano durante la infección por Haemophilus influenzae no tipable [PDF]
En esta Tesis Doctoral, hemos caracterizado el papel de un conjunto de estructuras de la superficie de Haemophilus influenzae (HiNT) como factores de virulencia implicados a distintos niveles del proceso infeccioso, mediante el empleo de mutantes ...
Departament de Biologia +1 more
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La accesión invertida: su génesis y evolución en la Jurisprudencia [PDF]
, 2009 Supuesto en nuestro Derecho un vacío legal en materia de construcciones extralimitadas (hechas en suelo en parte ajeno y en parte propio), consolidada jurisprudencia, desde la famosa STS de 31 mayo 1949, ha venido a colmarlo con la conocida accesión ...
Cerdeira Bravo de Mansilla, Guillermo
core
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source