Results 131 to 140 of about 993,133 (247)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The invasion of the sands : projects to clean the moat of fort Saint Fernando in Cartagena of Indias [PDF]

open access: yes, 2017
El presente artículo analiza las soluciones propuestas por distintos militares españoles para reparar uno de los principales problemas que afectaba a la conservación de las fortificaciones de Cartagena de Indias: la invasión de las arenas del foso del ...
Gámez Casado, Manuel
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

La primera Guerra de Chechenia en la pantalla: el prisionero de las montañas (2006)

open access: yesHistoria Actual On-Line, 2012
El cine se ha convertido en uno de los elementos más recurrentes a la hora de establecer historias no oficiales y radiografiar sociedades trastocadas por los diversos conflictos que han ido aflorando en las diversas regiones del mundo. En este caso, este
Igor Barrenetxea Marañón
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Caracterización de cepas de Listeria monocytogenes realizados a partir de queso fresco proveniente de diferentes zonas productoras costarricenses

open access: yesArchivos Latinoamericanos de Nutrición
En Costa Rica, cerca del 25% de la producción de leche nacional es utilizada en la elaboración de queso tierno no pasteurizado, y el consumo de este producto es aproximadamente de 4 a 5 kg anuales per cápita.
Carolina Cháves, María Laura Arias
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Determinación de los niveles de competencia para entrenamiento básico en microcirugía

open access: yesRevista Colombiana de Cirugía
Introducción. El nivel de competencia es la medida de las habilidades y destrezas que un estudiante debe desarrollar. Con base en ello, nuestro objetivo es determinar los parámetros que permitan evaluar el desempeño de cada participante frente a las ...
Francisco José Camacho   +1 more
doaj  

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