Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Validation and clinical application of molecular methods for the identification of molds in tissue [PDF]
, 2006 Background. Invasive fungal infections due to less-common molds are an increasing problem, and accurate diagnosis is difficult.Methods. We used our previously established molecular method, which allows species identification of molds in histological ...
Potter, M +6 more
core
Ratiometric Mycotoxin Detection in Living Plants With Dual‐Emissive Nanosensors
Advanced Materials, EarlyView.A minimally invasive microneedle patch integrates carbon dot‐embedded metal–organic frameworks as nanosensors to detect a key fungal toxin in living plants. The nanosensor produces a ratiometric fluorescence signal that enables early, non‐destructive diagnosis of fungal infection before visible symptoms, offering a new biomaterials‐based strategy for ...
Yuliang Li +9 more
wiley +1 more source
Invasive fungal infections in critically ill children: epidemiology, risk factors and antifungal drugs [PDF]
Background: Invasive fungal infections (IFIs) are important infectious complications amongst critically ill children. The most common fungal infections are due to Candida species.
Alexander KC Leung +4 more
core +1 more source
Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungi [PDF]
, 2008 Background: In contrast to the increasing numbers of agents for the treatment of invasive fungal infections, discoveries of new antifungal agents with therapeutic value in dermatomycoses are reported only rarely.
Borelli, Claudia +10 more
core +1 more source
Antifungal resistance, combinations and pipeline: oh my!
Drugs in Context, 2023 Invasive fungal infections are a strong contributor to healthcare costs, morbidity and mortality, especially amongst hospitalized patients. Historically, Candida was responsible for approximately 15% of all nosocomial bloodstream infections.
Kayla R Stover +4 more
doaj +1 more source
Invasive fungal infections in liver transplantation [PDF]
International Journal of Infectious Diseases, 2011 Invasive fungal infections (IFIs) in immunocompromised patients, particularly liver transplant recipients, are the subject of increasing clinical attention. Although the overall incidence of fungal infections in liver transplant recipients has declined due to the early treatment of high-risk patients, the overall mortality rate remains high ...
Liu, Xia +3 more
openaire +2 more sources
3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress
Advanced Materials Technologies, EarlyView.Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi +4 more
wiley +1 more source
Prognostic Factors of Cirrhotic Patients with Invasive Fungal Infections [PDF]
Fungal infection (FI) is a life-threatening condition in cirrhotic patients. However, a population-based study is required to determine the short-term mortality of these patients.
Hung, Tsung-Hsing;Ko, Ping-Hung;Tsai, Chih-Chun;Wang, Chih-Ying;Lee, Hsing-Feng
core +1 more source
Fungal biofilm resistance [PDF]
, 2012 Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon +7 more
core +1 more source