Results 51 to 60 of about 25,711 (214)

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]

, 2020
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Mamouei, Zeinab, Shaw, Karen J, Singh, Shakti, Wiederhold, Nathan P   +8 more
core   +1 more source

Invasive Pulmonary Aspergillosis-mimicking Tuberculosis [PDF]

Clinical Infectious Diseases, 2015
Pulmonary tuberculosis is occasionally confused with invasive pulmonary aspergillosis (IPA) in transplant recipients, since clinical suspicion and early diagnosis of pulmonary tuberculosis and IPA rely heavily on imaging modes such as computed tomography (CT).
Sung-Han, Kim, Mi Young, Kim, Sun In, Hong, Jiwon, Jung, Hyun Joo, Lee, Sung-Cheol, Yun, Sang-Oh, Lee, Sang-Ho, Choi, Yang Soo, Kim, Jun Hee, Woo   +9 more
openaire   +2 more sources

Treatment of Aspergillosis. [PDF]

, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Pediatric Pulmonary and Thoracic Aspergillosis

Siriraj Medical Journal, 2020
Aspergillus infection can cause significant disease in an immunocompromised host and lungs are the most common site of infection. Various forms of aspergillus involving lung parenchyma have been described including aspergilloma, allergic bronchopulmonary
Preeyacha Pacharn, Punchama Pacharn, Chantima Rongviriyapanich, Thomas Bryce   +3 more
doaj  

Gut-derived fungemia due to Kodamaea ohmeri combined with invasive pulmonary aspergillosis: a case report

BMC Infectious Diseases, 2022
Background Kodamaea ohmeri is a rare pathogen with high mortality and is found among blood samples in a considerable proportion; however, gastrointestinal infection of K. ohmeri is extremely rare.
Zi-Mu Li, Yu-Kun Kuang, Yi-Fan Zheng, Pei-Hang Xu, Ji-Yu Wang, Run-Jing Gan, Hui-Xia Li, Li-Hong Bai, Can-Mao Xie, Ke-Jing Tang   +9 more
doaj   +1 more source

Microsatellite typing of avian clinical and environmental isolates of Aspergillus fumigatus [PDF]

, 2011
Aspergillosis is one of the most common causes of death in captive birds. Aspergillosis in birds is mainly caused by Aspergillus fumigatus, a ubiquitous and opportunistic saprophyte.
Beernaert, Lies, Dorrestein, Gerry M, Haesebrouck, Freddy, Klaassen, Corné HW, Martel, An, Pasmans, Frank, Van Waeyenberghe, Lieven, Vercammen, Francis, Verstappen, Frank   +8 more
core   +3 more sources

Histopathological Implications of Aspergillus Infection in Lung

Mediators of Inflammation, 2013
This paper opens with a discussion on the significance of invasive fungal infections in advanced contemporary medicine, with an emphasis on the intractability of disease management and the difficulties of diagnosis.
Naobumi Tochigi, Yoichiro Okubo, Tsunehiro Ando, Megumi Wakayama, Minoru Shinozaki, Kyoko Gocho, Yoshinobu Hata, Takao Ishiwatari, Tetsuo Nemoto, Kazutoshi Shibuya   +9 more
doaj   +1 more source

Elevated Rates of Ventilator-Associated Pneumonia and COVID-19 Associated Pulmonary Aspergillosis in Critically Ill Patients with SARS-CoV2 Infection in the Second Wave: A Retrospective Chart Review

Antibiotics, 2022
Due to multiple risk factors, the rate of ventilator-associated pneumonia in critically ill COVID-19 patients has been reported in a range of 7.6% to 86%. The rate of invasive pulmonary aspergillosis in this cohort has been reported at 4% to 30%.
Sean Boyd, Kai Sheng Loh, Jessie Lynch, Dhari Alrashed, Saad Muzzammil, Hannah Marsh, Mustafa Masoud, Salman Bin Ihsan, Ignacio Martin-Loeches   +8 more
doaj   +1 more source

Primary intestinal aspergillosis resulting in acute intestinal volvulus after autologous stem cell transplantation in a patient with relapsed non-Hodgkin lymphoma : report on a rare infectious complication and a review of the literature

, 2019
Objectives: Since primary intestinal aspergillosis is a severe infectious complication with a high morbidity and mortality in immunocompromised patients, we want to draw attention to this rare entity and the importance of early recognition.
Kennes, Soetkin, Kerre, Tessa, Van de Putte, Dirk, Van Dorpe, Jo, VAN HENDE, VANESSA, Vlummens, Philip   +5 more
core   +1 more source

Prevalence and fungal profile of pulmonary aspergillosis in immunocompromised and immunocompetent patients of a tertiary care hospital [PDF]

, 2014
Background: Aspergillus is a fungus which may present an array of pulmonary manifestations, depending on the patient’s immunological and physiological state. Although the incidence of pulmonary aspergillosis occurs primarily in immunocompromised patients
Prakash Ved, Mishra Prem P, Verma Shashi K, Sinha Shivani, Sharma Mahendra
core   +1 more source