Results 181 to 190 of about 8,047 (306)

Digital patient decision aids for endometriosis management: a scoping review protocol. [PDF]

BMJ Open
Pittet O, Delvallée M, Pluchino N, Selby KJ, Elwyn G, Durand MA.   +5 more
europepmc   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

A Narrative Review of Advancements in Magnetic Resonance Imaging (MRI) Technology: Evaluating the Shift From Helium-Cooled to Helium-Free Systems. [PDF]

Cureus
Alenezi MM, Alqahtani S, Alqahtani H, Alasmari S, Alyami N, Alenzi F, Alanazi SF.   +6 more
europepmc   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Collaboration is key for national preparedness: The hospital's role in whole blood rotation models. [PDF]

Transfusion
Bowers A, Braverman M, Baines E, Epley E, Jenkins D.   +4 more
europepmc   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Bridging the preparedness gap: a systematic review of recommended stockpile items for radiological and nuclear emergencies. [PDF]

BMC Emerg Med
Nocci M, Bortolin M, Hertelendy AJ, Shaikh EA, Davis T, Serale M, Ragazzoni L, Issa F, Romagnoli S, DiGregorio D, Franc JM, Kung JY, Voskanyan A, Ciottone G.   +13 more
europepmc   +1 more source

Architectural Types for Healing and Control. The Interplay of Architecture, Material Culture, and Therapeutic Practice

International Congress - XIII ABRILS DE L’HOSPITAL (Lisbon’2024) HOSPITAL MATERIAL CULTURE IN THE MIDDLE AND EARLY MODERN AGES. CONCEPTS AND MEANINGS President of the Sicentific and Organizer Commitee: Dra.
Fröhlich, Anja
core  

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

How can ethnobiology and ethnomedicine foster more applied and concrete solutions to safeguard medicinal systems of indigenous, Afro-descendant and local communities? [PDF]

J Ethnobiol Ethnomed
Odonne G, Zank S.
europepmc   +1 more source