Results 51 to 60 of about 2,016,887 (339)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Inventory control exercises pdf [PDF]

, 2009
Exercises and solutions in ...

core  

Identifying Urban Sources as Cause of Elevated Grass Pollen Concentrations using GIS and Remote Sensing [PDF]

, 2013
We examine here the hypothesis that during flowering, the grass pollen concentrations at a specific site reflect the distribution of grass pollen sources within a few kilometres of this site.We perform this analysis on data from a measurement campaign in
Becker, T., Bonlokke, J. H., Geels, C., Hertel, O., Lund University., Orby, P. V., Schlunssen, V., Sigsgaard, T., Skjoth, Carsten,, Sogaard, P., Sommer, J.   +10 more
core   +4 more sources

Rediscovery of Lycodon gammiei (Blanford, 1878) (Serpentes, Colubridae) in Xizang, China, with comments on its systematic position [PDF]

ZooKeys
Lycodon gammiei (Blanford, 1878), a rarely encountered species of Asian snake, is characterized by ambiguous systematics and biology. Based on a sole specimen of L.
Fu Shu, Bing Lyu, Keji Guo, Tong Zhang, Xiaoqi Mi, Li Li, Yayong Wu, Peng Guo   +7 more
doaj   +3 more sources

The Maximization Inventory

Judgment and Decision Making, 2012
AbstractWe present the Maximization Inventory, which consists of three separate scales: decision difficulty, alternative search, and satisficing. We show that the items of the Maximization Inventory have much better psychometric properties when compared to the original Maximization Scale (Schwartz et al., 2002).
Turner, Brandon M., Rim, Hye B., Betz, Nancy E., Nygren, Thomas E.   +3 more
openaire   +4 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

1998 Oregon Winery Report [PDF]

, 1999
This statewide survey report on Oregon wineries covers crush, equivalent wine production, inventory and equivalent inventory, and sales. The report also contains some comparisons of data for 1997 and 1998.
Kriesel, Ronald F., Marousek, Douglas C., Oregon Agricultural Statistics Service, Rowley, Homer K.   +3 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Effects of traditional harvest and burning on common camas (Camassia quamash) abundance in Northern Idaho: The potential for traditional resource management in a protected area wetland

Ecology and Evolution, 2021
The bulbs of common camas (Camassia quamash) were a staple food of Indigenous Peoples of western North America for millennia. Camas harvesting site productivity was encouraged through intense management.
Devin S. Stucki, Thomas J. Rodhouse, Ron J. Reuter   +2 more
doaj   +1 more source