Results 91 to 100 of about 155,620 (242)

Organelle Localization‐Induced Bio‐Orthogonal Polymerization (OLIBOP) for Photostable Super‐Resolution Live‐Cell Imaging

Advanced Healthcare Materials, EarlyView.
Organelle localization‐induced biorthogonal polymerization enables direct synthesis of photostable poly‐AIEgens within targeted organelles for super‐resolution live‐cell imaging. ABSTRACT Real‐time monitoring of dynamic biological processes demands fluorescent probes that can withstand prolonged light exposure without photobleaching—a critical ...
Gaeun Park, Sangpil Kim, Dohyun Kim, Injun Hwang, Ja‐Hyoung Ryu   +4 more
wiley   +1 more source

Weak consistency of the 1-nearest neighbor measure with applications to missing data

, 2019
When data is partially missing at random, imputation and importance weighting are often used to estimate moments of the unobserved population. In this paper, we study 1-nearest neighbor (1NN) importance weighting, which estimates moments by replacing ...
Sharpnack, James
core  

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Polypharmacy Associated with Cognitive Decline in Newly Diagnosed Parkinson’s Disease: A Cross-Sectional Study

Dementia and Geriatric Cognitive Disorders Extra, 2019
Aims: Polypharmacy is well known to affect cognitive function in community-dwelling older adults. However, the effect of polypharmacy on cognitive function in patients with newly diagnosed Parkinson’s disease remains unknown.
Nobuyuki Ishii, Hitoshi Mochizuki, Katsuya Sakai, Go Ogawa, Kazutaka Shiomi, Masamitsu Nakazato   +5 more
doaj   +1 more source

Model misspecification and bias for inverse probability weighting and doubly robust estimators

, 2017
In the causal inference literature an estimator belonging to a class of semi-parametric estimators is called robust if it has desirable properties under the assumption that at least one of the working models is correctly specified.
Pazzagli, Laura, Waernbaum, Ingeborg
core  

Modeling time‐varying exposure using inverse probability of treatment weights

Biometrical Journal, 2017
AbstractFor estimating the causal effect of treatment exposure on the occurrence of adverse events, inverse probability weights (IPW) can be used in marginal structural models to correct for time‐dependent confounding. The R package ipw allows IPW estimation by modeling the relationship between the exposure and confounders via several regression models,
Graffeo, Nathalie, Latouche, Aurélien, Geskus, Ronald, Chevret, Sylvie   +3 more
openaire   +6 more sources

Intelligent Acousto‐Electrical Metamaterials (IAM) for Sound Source Detection

Advanced Materials, EarlyView.
Our proposed metamaterial concept enables sound source detection using a single material, in contrast to conventional arrays that require dozens or even hundreds of transducers. We show that the coupled acoustic–vibrational–electrical responses in piezoelectric metamaterials give rise to topology‐governed charge transport, producing distinct voltage ...
Victor Couëdel, Haotian Lu, Jiayan Zhang, Desheng Yao, Ananya Bhardwaj, Ramiro Contreras, Karim Sabra, Xiaoyu (Rayne) Zheng   +7 more
wiley   +1 more source

Influence of moderate left subclavian artery stenosis on outcomes after coronary bypass surgery in patients requiring hemodialysisCentral MessagePerspective

JTCVS Open
Objectives: Left subclavian artery stenosis in patients requiring hemodialysis can cause coronary steal syndrome via the left internal thoracic artery (LITA) graft to the left anterior descending artery (LAD), potentially leading to graft failure.
Ryoma Oda, MD, PhD, Takeshi Kinoshita, MD, PhD, Daisuke Endo, MD, PhD, Kan Kajimoto, MD, PhD, Taira Yamamoto, MD, PhD, Atsushi Amano, MD, PhD, Minoru Tabata, MD, PhD   +6 more
doaj   +1 more source

Inverse Probability Weighted Generalised Empirical Likelihood Estimators: Firm Size and R&D Revisited [PDF]

The inverse probability weighted Generalised Empirical Likelihood (IPW-GEL) estimator is proposed for the estimation of the parameters of a vector of possibly non-linear unconditional moment functions in the presence of conditionally independent sample ...
Inkmann, J.
core   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source