Results 71 to 80 of about 1,818,334 (300)

Demystifying stabilization in inverse probability of treatment weighting

Journal of Biopharmaceutical Statistics
Inverse probability of treatment weighting (IPTW) is a common approach to infer causal treatment effects when covariates are imbalanced at baseline or over time among treatment groups. One limitation of the IPTW is that a few observations with large weights can disproportionately influence inference, leading to dramatically increased variability in ...
Yong, Ma, Andrew, Giffin, Jiwei, He, Hana, Lee   +3 more
openaire   +2 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Comparative effectiveness and safety of low-dose and standard-dose rivaroxaban after inverse probability of treatment weighting.

, 2022
Comparative effectiveness and safety of low-dose and standard-dose rivaroxaban after inverse probability of treatment weighting.
Sylvie Perreault (3574211), Brian White-Guay (9507520), Marc Dorais (3467570), Aurélie Lenglet (138547), Alice Dragomir (669865), Robert Côté (10224343)   +5 more
core   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

G-computation and doubly robust standardisation for continuous-time data: a comparison with inverse probability weighting [PDF]

, 2021
In time-to-event settings, g-computation and doubly robust estimators are based on discrete-time data. However, many biological processes are evolving continuously over time.
Foucher, Yohann, Borgne, Florent Le, Leyrat, Clémence, Chatton, A., Borgne, F. Le, Leyrat, C., Foucher, Y., Chatton, Arthur, Clémence Leyrat, Arthur Chatton, Yohann Foucher, Florent Le Borgne   +11 more
core   +1 more source

Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The optimal antiplatelet regimen after standard endovascular aneurysm repair (EVAR) in patients without atherosclerotic cardiovascular disease remains uncertain.
Ki Hong Choi, Danbee Kang, Jihee Nam, Take Kyu Park, Myung Gyu Song, Tae‐Seok Seo, Woo Jin Yang, Seung‐Hyuk Choi   +7 more
doaj   +1 more source

Healthy and unhealthy plant‐based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes

Clinical and Translational Medicine, 2022
Background Plant‐based foods have been recommended for health. However, not all plant foods are healthy, and little is known about the association between plant‐based diets and specific molecular subtypes of colorectal cancer (CRC).
Fenglei Wang, Tomotaka Ugai, Koichiro Haruki, Yi Wan, Naohiko Akimoto, Kota Arima, Rong Zhong, Tyler S. Twombly, Kana Wu, Kanhua Yin, Andrew T. Chan, Marios Giannakis, Jonathan A. Nowak, Jeffrey A. Meyerhardt, Liming Liang, Mingyang Song, Stephanie A. Smith‐Warner, Xuehong Zhang, Edward L. Giovannucci, Walter C. Willett, Shuji Ogino   +20 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Association of COVID-19 infection during pregnancy with maternal and neonatal adverse outcomes using stabilized inverse probability of treatment weighting.

, 2023
Association of COVID-19 infection during pregnancy with maternal and neonatal adverse outcomes using stabilized inverse probability of treatment weighting.
Whanhee Lee (4421353), Choong-jong Kim (15333228), Jongmin Oh (15333225), Ji Hyen Lee (15333234), Hyesook Park (3554003), Eunhee Ha (5117687), Seulbi Lee (7505612), Yi Jun Kim (15333231), Mi Hye Park (7482950), Kyung A. Lee (15333237)   +9 more
core   +1 more source

Effect of Fluoroscopy‐Only Versus Transesophageal Echocardiography/Intracardiac Echocardiography Guidance in Left Atrial Appendage Occlusion on Stroke Prevention: Analysis From the RECORD I Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evidence regarding the link between imaging modality and stroke prevention outcomes of left atrial appendage occlusion is currently lacking.
Ping Wang, Zhengquan Chen, Yongmeng Yan, Guotao Fu, Jianzheng Liu, Ruining Zhang, Zhongbao Ruan, Xianxian Zhao, Haixiong Wang, Baopeng Tang, Xuegang Xie, Fu Yi, Yuan Bai, Xianhui Zhou, Junguo Zhu, Hongde Hu, Scot Garg, Patrick W. Serruys, Chao Gao, Ling Tao   +19 more
doaj   +1 more source