Results 41 to 50 of about 155,620 (242)

Utility of inverse probability weighting in molecular pathological epidemiology [PDF]

European Journal of Epidemiology, 2017
As one of causal inference methodologies, the inverse probability weighting (IPW) method has been utilized to address confounding and account for missing data when subjects with missing data cannot be included in a primary analysis. The transdisciplinary field of molecular pathological epidemiology (MPE) integrates molecular pathological and ...
Li, Liu, Daniel, Nevo, Reiko, Nishihara, Yin, Cao, Mingyang, Song, Tyler S, Twombly, Andrew T, Chan, Edward L, Giovannucci, Tyler J, VanderWeele, Molin, Wang, Shuji, Ogino   +10 more
openaire   +2 more sources

Association between delirium and statin use in patients with congestive heart failure: a retrospective propensity score-weighted analysis

Frontiers in Aging Neuroscience, 2023
BackgroundThe relationship between statin use and delirium remains controversial; therefore, we aimed to study the association between statin exposure and delirium and in-hospital mortality in patients with congestive heart failure.MethodsIn this ...
Jiangling Xia, Leilei Wang, Nannan Zhang, Hongyu Xu   +3 more
doaj   +1 more source

Discontinuous Parameter Estimates with Least Squares Estimators [PDF]

, 2013
We discuss weighted least squares estimates of ill-conditioned linear inverse problems where weights are chosen to be inverse error covariance matrices.
Mead, J. L.
core   +2 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Inverse probability weighting for causal inference in hierarchical data

BMC Medical Research Methodology
Objective The aim of this study was to explore the impact of model misspecification, balance, and extreme weights on average treatment effect (ATE) estimation in hierarchical data with unmeasured cluster-level confounders using the multilevel propensity ...
Lin Hu, Jie Yu, Chunxia Yang, Miaoshuang Chen, Zihuan Tang, Rujun Liao, Chunnong Jike, Ju Wang, Ruobing Wang, Qiang Liao, Tao Zhang   +10 more
doaj   +1 more source

Modeling Secondary Phenotypes Conditional on Genotypes in Case–Control Studies

Stats, 2022
Traditional case–control genetic association studies examine relationships between case–control status and one or more covariates. It is becoming increasingly common to study secondary phenotypes and their association with the original covariates.
Naomi C. Brownstein, Jianwen Cai, Shad Smith, Luda Diatchenko, Gary D. Slade, Eric Bair   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A Bayesian view of doubly robust causal inference [PDF]

, 2016
In causal inference confounding may be controlled either through regression adjustment in an outcome model, or through propensity score adjustment or inverse probability of treatment weighting, or both. The latter approaches, which are based on modelling
Belzile, Léo R., Saarela, Olli, Stephens, David A.   +2 more
core   +2 more sources

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Impact of Adopting Improved Seeds on Access to Broader Food Groups Among Small-Scale Sorghum Producers in Tanzania

SAGE Open, 2021
In this study, we use double-robust estimators (i.e., inverse probability weighting and inverse probability weighting with regression adjustment) to quantify the effect of adopting climate-adaptive improved sorghum varieties on household and women ...
Aloyce R. Kaliba, Anne G. Gongwe, Kizito Mazvimavi, Ashagre Yigletu   +3 more
doaj   +1 more source