Results 61 to 70 of about 55,893 (253)
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Neurodegenerative diseases, including Alzheimer's disease (AD), pose significant challenges to global healthcare because of their irreversible postsymptomatic progression. Conventional radiographic techniques have limitations in early detection, owing to
Hyo Lee +8 more
doaj +1 more source
Impact of Combustible Linings in the Simulated Fluid Dynamics of a Compartment Fire
The increasing use of engineered timber in modern architecture raises critical concerns about fire safety, particularly when combustible linings are exposed within compartments.
Ignacio Calderón +2 more
doaj +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Water‐Immersed GaP Huygens’ Meta‐Optics for Visible Structured Light Generation
Underwater photonics is essential for imaging and analysis in biomedical technologies, as well as for communication and autonomous vehicle networks in the Internet of Underwater Things (IoUT).
Jia‐Hua Lee +8 more
doaj +1 more source
Heterogeneity of the tumor microenvironment (TME) within and among patients with liver cancer has significant effects on their responses to therapies. Systematic and detailed characterization of the TME can guide precision therapy.
Yacan Zhao, Yibo Huang
doaj +1 more source
As an important advanced technique in the field of Earth observations, Synthetic Aperture Radar (SAR) plays a key role in the study of global environmental change, resources exploration, disaster mitigation, urban environments, and even lunar exploration.
Huadong Guo +18 more
openaire +2 more sources
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source

