Stochastic modeling error reduction using Bayesian approach coupled with an adaptive kriging based model [PDF]
, 2012 Magnetic material properties of an electromagnetic device can be recovered by solving an inverse problem where measurements are adequately interpreted by a mathematical forward model.
Dupré, Luc +1 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 2023 All the Python codes and data to reproduce the results of 'Groundwater inverse modeling: physics-informed neural network with separable constraints and errors'.
openaire +1 more source
Applications of inverse simulation to a nonlinear model of an underwater vehicle [PDF]
, 2008 Inverse simulation provides an important alternative to conventional simulation and to more formal mathematical techniques of model inversion. The application of inverse simulation methods to a nonlinear dynamic model of an unmanned underwater ...
Lu, L., McGookin, E., Murray-Smith, D.
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Local Analysis of Inverse Problems: H\"{o}lder Stability and Iterative Reconstruction
, 2012 We consider a class of inverse problems defined by a nonlinear map from parameter or model functions to the data. We assume that solutions exist. The space of model functions is a Banach space which is smooth and uniformly convex; however, the data space
Ammari H +12 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Multiscale Modelling and Inverse Problems [PDF]
, 2011 Submitted to the proceedings of the summer school "Numerical Analysis of Multiscale Problems", edited by I.G. Graham, T.Y. Hou, O. Lakkis and R. Scheichl.
Nolen, James +2 more
openaire +3 more sources
A model realizing inverse seesaw and resonant leptogenesis
, 2015 We construct a model realizing the inverse seesaw mechanism. The model has two types of gauge singlet fermions in addition to right-handed neutrinos.
Aoki, Mayumi +2 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source