Results 71 to 80 of about 1,854,472 (300)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Healthy and unhealthy plant‐based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes

Clinical and Translational Medicine, 2022
Background Plant‐based foods have been recommended for health. However, not all plant foods are healthy, and little is known about the association between plant‐based diets and specific molecular subtypes of colorectal cancer (CRC).
Fenglei Wang, Tomotaka Ugai, Koichiro Haruki, Yi Wan, Naohiko Akimoto, Kota Arima, Rong Zhong, Tyler S. Twombly, Kana Wu, Kanhua Yin, Andrew T. Chan, Marios Giannakis, Jonathan A. Nowak, Jeffrey A. Meyerhardt, Liming Liang, Mingyang Song, Stephanie A. Smith‐Warner, Xuehong Zhang, Edward L. Giovannucci, Walter C. Willett, Shuji Ogino   +20 more
doaj   +1 more source

Demystifying stabilization in inverse probability of treatment weighting

Journal of Biopharmaceutical Statistics
Inverse probability of treatment weighting (IPTW) is a common approach to infer causal treatment effects when covariates are imbalanced at baseline or over time among treatment groups. One limitation of the IPTW is that a few observations with large weights can disproportionately influence inference, leading to dramatically increased variability in ...
Yong, Ma, Andrew, Giffin, Jiwei, He, Hana, Lee   +3 more
openaire   +2 more sources

The Kaplan–Meier Estimator as an Inverse-Probability-of-Censoring Weighted Average [PDF]

The American Statistician, 2001
The Kaplan-Meier (product-limit) estimator of the survival function of randomly-censored time-to-event data is a central quantity in survival analysis. It is usually introduced as a nonparametric maximum likelihood estimator, or else as the output of an imputation scheme for censored observations such as redistribute-to-the-right or self-consistency ...
Satten G. A., Datta S.
openaire   +3 more sources

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The optimal antiplatelet regimen after standard endovascular aneurysm repair (EVAR) in patients without atherosclerotic cardiovascular disease remains uncertain.
Ki Hong Choi, Danbee Kang, Jihee Nam, Take Kyu Park, Myung Gyu Song, Tae‐Seok Seo, Woo Jin Yang, Seung‐Hyuk Choi   +7 more
doaj   +1 more source

Per-protocol analysis of the ZINC trial for HIV disease among alcohol users

Trials, 2021
Background The Zinc for INflammation and Chronic disease in HIV (ZINC) trial randomized person who live with HIV (PLWH) who engage in heavy drinking to either daily zinc supplementation or placebo.
Sara Lodi, Matthew Freiberg, Natalia Gnatienko, Elena Blokhina, Tatiana Yaroslavtseva, Evgeny Krupitsky, Eleanor Murray, Jeffrey H. Samet, Debbie M. Cheng   +8 more
doaj   +1 more source

Association of COVID-19 infection during pregnancy with maternal and neonatal adverse outcomes using stabilized inverse probability of treatment weighting.

, 2023
Association of COVID-19 infection during pregnancy with maternal and neonatal adverse outcomes using stabilized inverse probability of treatment weighting.
Whanhee Lee (4421353), Choong-jong Kim (15333228), Jongmin Oh (15333225), Ji Hyen Lee (15333234), Hyesook Park (3554003), Eunhee Ha (5117687), Seulbi Lee (7505612), Yi Jun Kim (15333231), Mi Hye Park (7482950), Kyung A. Lee (15333237)   +9 more
core   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Effect of Fluoroscopy‐Only Versus Transesophageal Echocardiography/Intracardiac Echocardiography Guidance in Left Atrial Appendage Occlusion on Stroke Prevention: Analysis From the RECORD I Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evidence regarding the link between imaging modality and stroke prevention outcomes of left atrial appendage occlusion is currently lacking.
Ping Wang, Zhengquan Chen, Yongmeng Yan, Guotao Fu, Jianzheng Liu, Ruining Zhang, Zhongbao Ruan, Xianxian Zhao, Haixiong Wang, Baopeng Tang, Xuegang Xie, Fu Yi, Yuan Bai, Xianhui Zhou, Junguo Zhu, Hongde Hu, Scot Garg, Patrick W. Serruys, Chao Gao, Ling Tao   +19 more
doaj   +1 more source