Results 11 to 20 of about 277,071 (205)

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Determinantes de la inversión extranjera directa China en Latinoamérica

Quipukamayoc, 2020
Objetivo: Analizar el flujo de inversión extranjera directa de la República Popular China desde el 2008 al 2017 en 7 países latinoamericanos: Argentina, Brasil, Chile, Colombia, México, Perú y Uruguay. Método: La investigación es de tipo cuantitativo, no
Luis Alfredo Ávila-López, Jorge Alfonso Galván-León, Carolina Zayas-Márquez   +2 more
doaj   +1 more source

"El inglés me hizo sentirme orgulloso de mí mismo":

CLIL Journal of Innovation and Research in Plurilingual and Pluricultural Education, 2022
Este estudio de caso pretende hacer un seguimiento longitudinal de cómo evolucionan las identidades imaginadas como usuarios de inglés de dos estudiantes de magisterio durante el Grado de Educación Primaria en inglés (EMI-TED) ofrecido por una ...
Natalia Evnitskaya, Berta Torras Vila
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Transferencia de riesgos en la cadena de valor de la manzana de exportación

UCMaule, 2015
Esta investigación describe, en el contexto de la globalización alimentaria, la transferencia de riesgos producida desde el escenario global al local, a partir de la interacción económica entre un packing exportador y una empresa productora de manzanas ...
Leonardo Alfredo Soto Troncoso
doaj  

Bonos verdes versus bonos convencionales: ¿existe una demanda diferenciada en México?

The Anáhuac Journal, 2019
¿Es la demanda de bonos verdes diferente a la demanda de bonos convencionales? A partir del estudio seminal de Fama y French (2007) quienes consideraron que la demanda de activos financieros, además de criterios de rendimiento y riesgo, podría explicarse
Rogelio Arellano Cadena, Lucía Pérez Delgado   +1 more
doaj   +1 more source