Results 41 to 50 of about 694,399 (289)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Classifying-Inversion Method of Offshore Atmospheric Duct Parameters Using AIS Data Based on Artificial Intelligence

Remote Sensing, 2022
Atmospheric duct parameters inversion is an important aspect of microwave-band radar and communication system performance evaluation. AIS (Automatic Identification System) is one of the signal sources used for atmospheric duct parameters inversion ...
Jie Han, Jiaji Wu, Lijun Zhang, Hongguang Wang, Qinglin Zhu, Chao Zhang, Hui Zhao, Shoubao Zhang   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Theory of Fulde-Ferrell-Larkin-Ovchinnikov state of superconductors with and without inversion symmetry: Hubbard model approach

, 2007
We study Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) state of superconductors with and without inversion symmetry based on the Hubbard model on the square lattice near half-filling, using the random phase approximation.
Adachi H., Agterberg D. F., Agterberg D. F., Akazawa T., Aoki H., Asano Y., Barzykin V., Bauer E., Bauer E., Bergeret F. S., Bianchi A., Bianchi A., Bonalde I., Braude V., Burkhardt H., Buzdin A. I., Buzdin A. I., Capan C., Casalbuoni R., Correa V. F., Demmel J., Dimitrova O. V., Edelstein V. M., Frigeri P. A., Fujimoto S., Fujimoto S., Fujimoto S., Fujimoto S., Fulde P., Gao B.-L., Gor'kov L. P., Hall D., Hayashi N., Iniotakis C., Izawa K., Izawa K., Kadigrobov A., Kakuyanagi K., Kaur R. P., Kimura N., Kumagai K., Larkin A. I., Maki K., Matsuda Y., Matsuo S., Miclea C. F., Mineev V. P., Mitrović V. F., Miyake K., Movshovich R., Onari S., Radovan H. A., Rashba E. I., Samokhin K. V., Samokhin K. V., Scalapino D. J., Sergienko I. A., Shimahara H., Shimahara H., Shimahara H., Shimahara H., Shimahara H., Sugitani I., Takada S., Tanaka H., Tanaka Y., Vorontsov A., Vorontsov A. B., Vorontsov A. B., Watanabe T., Watanabe T., Won H., Yanase Y., Yogi M., Yokoyama T., Yokoyama T., Yokoyama T.   +76 more
core   +1 more source

Ensemble Kalman filter for neural network based one-shot inversion

, 2020
We study the use of novel techniques arising in machine learning for inverse problems. Our approach replaces the complex forward model by a neural network, which is trained simultaneously in a one-shot sense when estimating the unknown parameters from ...
Guth, Philipp A., Schillings, Claudia, Weissmann, Simon   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Inferring the Variability of Dielectric Constant on the Moon from Mini-RF S-Band Observations

Remote Sensing
The physical properties of lunar regolith are crucial for exploration planning, hazard assessment, and characterizing scientific targets at global and polar scales. The dielectric constant, a key property, offers insights into lunar material distribution
Shashwat Shukla, Gerald Wesley Patterson, Abhisek Maiti, Shashi Kumar, Nicholas Dutton   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Estimating leaf mercury content in Phragmites australis based on leaf hyperspectral reflectance

Ecosystem Health and Sustainability, 2020
Introduction: High mercury (Hg) concentrations affect the chlorophyll in leaves, thereby modifying leaf spectra. Hyperspectra is a promising technique for the rapid, nondestructive evaluation of leaf Hg content. In this study, we investigated Hg contents
Weiwei Liu, Mengjie Li, Manyin Zhang, Daan Wang, Ziliang Guo, Songyuan Long, Si Yang, Henian Wang, Wei Li, Yukun Hu, Yuanyun Wei, Hongye Xiao   +11 more
doaj   +1 more source

Extended Seismic Source Characterisation using Linear Programming Inversion in a Dual Formulation [PDF]

, 2012
A linear programming (LP) inversion method in a dual formulation was applied to reconstruct the kinematics of finite seismic ruptures. In a general setting, this approach can yield results from several data sets: strong ground motion, teleseismic ...
Bezzeghoud, M., Borges, J.F., Bushenkov, V., Caldeira, B., Smirnov, G.   +4 more
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